Drug- and Toxin-Induced Liver Disease
Drug- and Toxin-Induced Liver Disease 14.1 Alcoholic Liver Disease Mayo Clin Proc 2001;76:1021; Postgrad Med J 2000;76:280 Cause: Excessive intake of ethanol. For practical purposes, alcohol has been defined in…
Neoplastic Liver Disease
Neoplastic Liver Disease 13.1 Hepatocellular Carcinoma Lancet 2003;362:1907; Postgrad Med J 2000;76:4 Cause: (Nejm 1999;340:798) The vast majority of cases of hepatocellular carcinoma (HCC) are due to chronic hep B…
Metabolic and Inflammatory Liver Disease
Metabolic and Inflammatory Liver Disease 12.1 Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Hepatology 2009;49:306; Nejm 2002;346:1221 Epidem: The prevalence of nonalcoholic fatty liver disease (NAFLD) is estimated between 10%…
Infections of the Liver
Infections of the Liver 11.1 Hepatitis A Lancet 1998;351:1643; Gastroenterologist 1996;4:107 Cause: The hep A virus, a small, nonenveloped RNA virus of the genus Hepatovirus. There are 4 stable human…
The Biliary Tree
The Biliary Tree 10.1 Cholecystitis and Biliary Colic Am Fam Phys 2000;61:1673; Clin Perspect Gastro 2000;March:87 Epidem: The risk of gallstones rises with age. The prevalence of gallstones in young…
Vascular Disorders of the Gut
Vascular Disorders of the Gut 8.1 Acute Mesenteric Ischemia BMJ 2003;326:1372; GE 2000;118:954 Cause: This catastrophic illness most commonly results from emboli, but it can also result from arterial or…
Anorectal Disorders
Anorectal Disorders 7.1 Hemorrhoids GE 2004;126:1463; Prim Care 1999;26:35 Epidem: The prevalence of hemorrhoids is 80-90% in U.S. adults, with equal prevalence in men and women (Dis Colon Rectum 1983;26:435)….
Infectious Intestinal Disorders
Infectious Intestinal Disorders Comment: The most frequently encountered infectious causes of diarrhea are summarized in Section 6.1. For a discussion of the diff dx, see Acute Diarrhea (p 14) or…
Neoplastic Intestinal Disorders
Neoplastic Intestinal Disorders 5.1 Colorectal Cancer GE 2000;118:S115; Lancet 1999;353:391 Epidem: (Gastroenterol Clin North Am 1996;25:717) Colorectal cancer (CRC) is the second-leading cause of cancer death in the U.S. Based…
