Biomarkers in Urologic Cancer
Kevin R. Loughlin, MD, MBA, Editor This issue of Urologic Clinics is devoted to biomarkers. The writer Sean O’Casey said, “Nothing is so powerful as an idea whose time has…
Biomarkers in Urologic Cancer
Samir S. Taneja, MD, Consulting Editor This wonderful issue of Urologic Clinics explores the current and evolving role of biomarkers in urologic oncology. While we often consider biomarkers only in…
Management of Hypogonadism in Cardiovascular Patients
Key points • Testosterone replacement therapy should only be prescribed to men with both clinical symptoms of androgen deficiency and unequivocally low testosterone levels. • Despite a relatively constant prevalence…
Trends in Testosterone Prescription and Public Health Concerns
Testosterone supplementation therapy (TST) has become increasingly popular since the turn of the century. Most prescriptions in the U.S. are written by primary care providers, endocrinologists, or urologists. The FDA…
Obesity and Hypogonadism
The relationship between obesity and hypogonadism is complicated. The relationship is bidirectional and there are numerous causative and correlative factors on both sides of the equation. Obesity is increasing in…
Testosterone Deficiency and Sleep Apnea
Key points • Obstructive sleep apnea (OSA) is associated with altered pituitary–gonadal function. • Serum testosterone (T) has been shown to be lower in men with OSA. • T supplementation…
Testosterone and Varicocele
Varicocele is defined as an excessive dilation of the pampiniform plexus. The association between varicocele and infertility has been well-established as evidenced by negative effects on spermatogenesis. Accumulating evidence now…
Testosterone and Sexual Function
Testosterone and sexual function are related. Current evidence suggests that testosterone replacement therapy (TRT) may improve sexual dysfunction. Sexual dysfunction in men who are hypogonadal, mixed, or eugonadal have all…
Testosterone Therapy and Prostate Cancer
Changes in understanding regarding the relationship of androgens and prostate cancer have led to changes in the use of testosterone therapy. The evidence supports a finite ability of androgens to…
Testosterone Deficiency and the Prostate
Male hormonal physiology plays an important role in the function and development of the prostate. Moreover, benign prostatic hyperplasia and prostate cancer, two common and bothersome conditions of the prostate,…
