Laparoscopic Nephrectomy and Partial Nephrectomy
The indication for use of laparoscopy, in the pediatric population, was initially for diagnostic purposes. As confidence with the technology and utility grew, it began to be applied for therapeutic…
Laparoscopic Orchiopexy and Varicocelectomy
The role of laparoscopy in the case of nonpalpable cryptorchidism is both diagnostic and therapeutic. Laparoscopic orchiopexy for nonpalpable testes in the pediatric population has become the preferred surgical approach…
Percutaneous Nephrolithotomy and Ureteroscopy in Children:
The increasing incidence of pediatric stone disease has coincided with significant advances in technology and equipment, resulting in drastic improvements in management. Miniaturization of both ureteroscopes and percutaneous nephrolithotomy (PCNL)…
Minimally Invasive Pediatric Urologic Surgery
Aseem R. Shukla, MD, FAAP, Editor While the practice of surgery advanced tremendously due to innovations in anesthesia, analgesia, and antibiotics over the past century, the advent of laparoscopy followed…
Minimally Invasive Pediatric Urologic Surgery
Samir S. Taneja, MD, Consulting Editor Pediatric Urology is truly a discipline of Urology unto itself. While most of us trained in the basics of the “bread-and-butter” procedures, the practice…
Targeted Therapy in Advanced Bladder Cancer
Despite advances in the treatment of other genitourinary malignancies, no novel therapies have been approved by the US Food and Drug Administration for urothelial carcinoma (UC) in the last 20 years….
Surgical Advances in Bladder Cancer
Bladder cancer is the most expensive cancer to treat from diagnosis to death. Frequent disease recurrence, intense follow-up, and expensive, invasive techniques for diagnosis and treatment drive these costs for…
Neoadjuvant Therapy in Muscle-Invasive Bladder Cancer
Since the advent of cisplatin-based combination therapy in the management of muscle-invasive and advanced bladder cancer, there has been little progress in improving outcomes for patients. Novel therapies beyond cytotoxic…
Novel Biomarkers to Predict Response and Prognosis in Localized Bladder Cancer
This review summarizes recent developments in diagnostic and prognostic biomarkers for nonmuscle invasive bladder cancer (NMIBC). Although the number of new biomarkers increases continuously, none are included in practice guidelines….
Potential Role for Targeted Therapy in Muscle-Invasive Bladder Cancer
The Cancer Genome Atlas project has identified and confirmed several important molecular alterations that form the basis for tumorigenesis and disease progression in muscle-invasive bladder cancer. Profiling studies also have…
