Cell Transplantation
Introduction For numerous liver diseases of childhood, liver transplantation (LT) is a lifesaving procedure. However, it requires scarce organs, a highly experienced team to manage the surgical procedure, complications, and…
Liver Assist Systems in Pediatric Liver Failure
Introduction Currently, the standard medical treatment (SMT) for pediatric liver failure incorporates optimal supportive care with hemodynamic and respiratory support, infection control, and avoidance of gastrointestinal bleeding, aiming to bridge…
Role of Biomarkers in Monitoring Liver Allograft Function
Introduction Over the past decades, survival rates after pediatric liver transplantation have increased from about 76% to over 90% more than 10 years after transplantation (Tx). Follow-up care of liver-transplanted…
Anti-infection Strategies
Anti-infection Strategies Infections are the cause of significant morbidity and mortality after transplantation, both in the immediate post-operative period and beyond ( Fig. 19.1 ). Anti-infection strategies include preventive measures,…
Post-Operative Care After Liver Transplantation
Introduction Liver transplantation (LT) is a major surgical procedure, with recipients presenting with end-stage liver disease and the complications thereof. It follows that post-operative care is complex and requires continuous…
Role of Radiology and Interventional Radiology After Pediatric Liver Transplantation
Diagnosis of Complications: Role of Imaging Modalities Systematic Follow-up Ultrasonography with Doppler (US Doppler) is the best imaging modality for systematic follow-up of the liver allograft and for the detection…
Early Vascular Complications
This chapter treats early vascular complications after pediatric liver transplantation (PLT), which herein will be defined as complications that occur during the first 4 weeks after liver transplantation (LT). General…
Post-transplant Lymphoproliferative Disease
Introduction Post-transplant lymphoproliferative diseases (PTLDs) are the most frequent malignant disorders after solid-organ transplantation in children. Although morphologically often indistinguishable from de novo lymphomatous diseases, per definition, every lymphoproliferation arising…
Role of Histology Following Pediatric Liver Transplantation
Introduction This chapter will briefly consider the examination of the recipient’s liver, removed at transplantation, and then focus on the role of the pathologist in the interpretation of the liver…
Surgical Complications
Introduction Long-term outcomes after pediatric liver transplantation are nowadays characterized by their excellence. Remarkably, when compared with older age group results, graft and patient midterm survival rates are higher, with…
