The Epidemiology of Acute Kidney Injury
Abstract Acute kidney injury (AKI) is characterized by sudden (i.e., hours to days) impairment of kidney function. AKI is an increasingly common complication in hospitalized individuals around the world and…
Recurrent and De Novo Renal Diseases After Kidney Transplantation
Abstract This chapter will review the recurrence and de novo presentation of renal diseases in the kidney transplant recipient. Primary glomerular, secondary glomerular, and nonglomerular disorders and their frequency and…
Surgical Management of the Renal Transplant Recipient
Abstract Kidney transplantation is now the standard of care for properly selected patients with end-stage renal disease. Successful transplantation provides remarkable improvement in quality of life and decreases recipient mortality…
Renal Replacement Therapy for Acute Kidney Injury
Abstract The indications, timing of initiation, and choice of modality and intensity of delivered therapy are factors that must be considered in prescribing renal replacement therapy (RRT) to patients with…
Pharmacological Interventions in Acute Kidney Injury
Abstract Translating advances in our understanding of the pathogenesis of acute kidney injury (AKI) to clinical trials require robust animal models for AKI, identification of targets for AKI relevant to…
Noninfectious Complications After Kidney Transplantation
Abstract Kidney transplantation is the treatment of choice for selected patients with end-stage renal disease (ESRD) because of improvements in patient survival, quality of life, and reduced long-term health costs….
Home Hemodialysis
Abstract Home hemodialysis allows for individualized therapy. It is an effective way to provide increased frequency, increased duration dialysis, or both. We explore the benefits and risk of the therapy…
Evaluation of Donors and Recipients
Abstract It is important to medically evaluate both living donor candidates and recipients for kidney transplantation to minimize surgical risks and to provide long-term health and survival. This chapter focuses…
Infection in Renal Transplant Recipients
Abstract Infections are a major cause of morbidity and mortality in renal transplant recipients. This chapter reviews major risk factors for infection as well as important preventive measures. More common…
Immunosuppressive Therapy
Abstract: Significant advances have been made in the field of transplantation since the first successful kidney transplant between identical twins in 1954. A better understanding of immunobiology and immunosuppression not…
