Diagnosis of Barrett’s Esophagus

Feb 12, 2019 by in GASTROENTEROLOGY Comments Off on Diagnosis of Barrett’s Esophagus

Abstract Barrett’s esophagus is a condition in which normal stratified squamous epithelium of the esophagus is replaced with columnar epithelium. It is the primary precursor lesion for esophageal adenocarcinoma and…

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Fluctuating Risk Factors and Epidemiology

Feb 12, 2019 by in GASTROENTEROLOGY Comments Off on Fluctuating Risk Factors and Epidemiology

Abstract Barrett’s esophagus (BE) is an acquired condition associated with severe gastroesophageal reflux disease (GERD) and has a malignant predisposition. The overall prevalence of BE in general population varies between…

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A Disease Entity Is Identified

Feb 12, 2019 by in GASTROENTEROLOGY Comments Off on A Disease Entity Is Identified

Abstract Barrett’s esophagus (BE) is the presence of metaplastic columnar epithelium in the lower portion of the esophagus, which is normally lined with stratified squamous epithelium. The main cause of…

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Overview of Therapy for Glomerular Disease

Feb 6, 2019 by in NEPHROLOGY Comments Off on Overview of Therapy for Glomerular Disease

Chapter Outline THE GLOBAL IMPACT AND CHALLENGES, 1161 OUTCOME MEASURES AND CLINICAL TRIALS IN GLOMERULONEPHRITIS, 1163 QUANTIFICATION OF THE BENEFITS OF PROTEINURIA REDUCTION, 1163 Membranous Glomerulonephritis, 1164 Focal Segmental Glomerulosclerosis,…

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Biomarkers in Acute and Chronic Kidney Diseases

Feb 6, 2019 by in NEPHROLOGY Comments Off on Biomarkers in Acute and Chronic Kidney Diseases

Chapter Outline BIOMARKER DEFINITION, 927 PROCESS OF BIOMARKER DISCOVERY, ASSAY VALIDATION, AND QUALIFICATION IN A CLINICAL CONTEXT, 927 Phase 1: Discovery of Potential Biomarkers through Hypothesis-Generating Exploratory Studies, 927 Phase…

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Biomarkers in Acute and Chronic Kidney Diseases

Feb 6, 2019 by in NEPHROLOGY Comments Off on Biomarkers in Acute and Chronic Kidney Diseases

Chapter Outline BIOMARKER DEFINITION, 927 PROCESS OF BIOMARKER DISCOVERY, ASSAY VALIDATION, AND QUALIFICATION IN A CLINICAL CONTEXT, 927 Phase 1: Discovery of Potential Biomarkers through Hypothesis-Generating Exploratory Studies, 927 Phase…

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The Kidney Biopsy

Feb 6, 2019 by in NEPHROLOGY Comments Off on The Kidney Biopsy

Chapter Outline SAFETY AND COMPLICATIONS OF BIOPSIES, 915 PERFORMING THE BIOPSY, 918 BIOPSY SPECIMEN HANDLING, 919 LIGHT MICROSCOPY, 919 Staining for Light Microscopy, 919 Examination of the Biopsy Specimen by…

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