Overall Bottom Line Success in liver transplantation depends on coordination of care among a multidisciplinary team. Initial assessment should start with careful review of the entire patient history including details…
Overall Bottom Line HE is a myriad of complex neuropsychiatric symptoms occurring in patients with significant liver dysfunction. It occurs most commonly in patients with cirrhosis, but can be a…
Overall Bottom Line BCS is a vascular disorder of the liver causing outflow obstruction of blood flow. BCS can present as an acute fulminant hepatic failure with massive hepatic necrosis…
Overall Bottom Line Pregnancy-specific liver diseases are the most common cause of abnormal liver tests in pregnancy. It is imperative to evaluate for pre-existing or newly acquired liver disease (viral…
Overall Bottom Line The term LFTs is often misused to refer to serum chemistry tests. Liver disease is evaluated by tests that detect liver injury, impaired bile flow or cholestasis,…
Overall Bottom Line PSC is a cholestatic liver disease characterized by inflammation and fibrosis of the biliary system that can result in the formation of multifocal biliary strictures. Though the…
Overall Bottom Line Alpha-1 antitrypsin (AAT) deficiency is an inherited disease primarily affecting the lungs and liver, which is most often due to a defect in the release of AAT…
Overall Bottom Line HIV co-infection accelerates both hepatitis C and hepatitis B natural history leading to faster progression to and increased incidence of cirrhosis, HCC and death. HIV/HCV co-infected patients…
Overall Bottom Line HRS is a potentially reversible functional renal insufficiency in patients with cirrhosis, advanced liver failure and portal hypertension. There is no specific diagnostic test for HRS. The…
Overall Bottom Line PBC is a slowly progressive autoimmune liver disease that causes destruction to the small- and medium-sized intrahepatic bile ducts. Most patients with PBC are diagnosed after abnormal…
