Indications and Timing
Fig. 15.1 Natural history of renal disease To determine the timing, i.e., when to proceed to transplantation, a distinction must be made between theory and practice. In theory, transplant should…
Postoperative Technical Complications
Fig. 12.1 Percutaneous transhepatic cholangiography showing typical findings of intrahepatic biliary dilatation and stenosis, “cast syndrome,” due to posttransplant hepatic thrombosis. Early surgical revascularization was performed, but the patient required…
Anaesthetic and Perioperative Management for Liver Transplantation
Hepatic Renal electrolyte glucose Cardiovascular Pulmonary Neurologic Haematologic Decreased metabolic function Acute kidney injury Vasodilated state Aspiration risk Hepatic encephalopathy Bleeding and thrombosis Decreased gluconeogenesis Hepatorenal syndrome Hyperdynamic cardiac function…
Liver Procurement
Category Description I Dead on arrival: corneas, heart valves, skin, bone, etc., can be recovered since there are no immediate time constraints to minimize tissue injury and there is no…
Infection Complications After Abdominal Organ Transplantation
Greater infectious risk Critical illness entering transplantation Prior colonization with antimicrobial-resistant pathogens Induction therapy – lymphocyte depletion High-dose corticosteroids Plasmapheresis (not well studied) High rejection risk (HLA mismatch desensitization) Early…
Transplantation Immunology
Fig. 1.1 Structure of mTOR inhibitors, everolimus (left), and sirolimus (right). Everolimus differs from sirolimus due to the addition of a 2-hydroxyethyl group at C40 Table 1.1 mTOR inhibitors –…
Indications for Liver Transplantation
Acetaminophen-induced ALF Nonacetaminophen ALF Arterial pH <7.3 irrespective of grade of encephalopathy or INR >6.5 (PT >100 s), irrespective of grade of encephalopathy PT >100 s Or any 3 of…
Medical Disease After Abdominal Solid Organ Transplantation and the Risk of Solid and Hematologic Malignant Tumor After Transplantation
Adverse effect Cyclosporine Tacrolimus Steroids Aza Mycophenolate mofetil Sirolimus-everolimus Arterial hypertension +++ ++ +++ − − + Hyperglycemia − + +++ − − − Hyperlipidemia ++ + ++ − −…
The Safety of Donor
© Springer International Publishing Switzerland 2015Antonio Daniele Pinna and Giorgio Ercolani (eds.)Abdominal Solid Organ Transplantation10.1007/978-3-319-16997-2_4 4. The Safety of Donor Antonia D’Errico1 , Deborah Malvi1 and Francesco Vasuri1 (1) “F. Addarii” Institute of Oncology and Transplant Pathology, S. Orsola…
Origin and Pathophysiology
Fig. 2.1 Illustration depicting the venous testicular vasculature (a), and the drainage of right and left testes (b). The right testicular vein empties into the inferior vena cava while the…
