Gastrointestinal diseases Celiac disease Crohn’s disease Ulcerative colitis Hepatic diseases Alcoholic liver disease Hepatic B viral infections Chronic schistosomiasis Cryptogenic cirrhosis Primary biliary cirrhosis Portosystemic shunts Autoimmune diseases Granulomatosis with…
(1) Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA (2) Division of Hematology, Mayo Clinic, Rochester, MN, USA Abstract Amyloidosis is a group of diseases characterized by…
Fig 25.1 Voiding cystourethrogram revealed right vesicoureteral reflux to blunted calices (not shown). Images provided by Dr. Akira Kawashima, Department of Radiology, Mayo Clinic, Rochester, MN Fig 25.2 Delayed enhanced…
Fig. 24.1 Simplistic schematic representation of the general relationship between inflammatory cells (resident and infiltrating), vessels, fibroblasts, tubules and extracellular matrix in the normal kidney. The interrelation and interaction between…
Fig. 7.1 Skin histology. Cryoglobulinemic vasculitis with fibrinoid necrosis of the capillary walls with pyknotic nuclei and nuclear debris of granulocytes and mononuclear cell infiltrates Rheumatologic Manifestations. Arthralgias, usually bilateral…
Anti-GBM disease ANCA-associated vasculitis • May present with rapidly progressive renal failure and anuria • Systemic prodromal symptoms are uncommon • Dialysis dependency at presentation rarely associated with renal recovery…
Fig. 11.1 The pathogenesis of lupus nephritis and novel therapies based on pathogenic pathways. In this model lupus nephritis begins with the accumulation of autoreactive self-antigens such as nucleosomes. The…
Fig. 14.1 Renal biopsy showing a large cell with CMV inclusions and surrounding interstitial inflammation (H&E, 60×) Fig. 14.2 Immunohistochemistry (immunoperoxidase staining) showing CMV-infected cells Other Immunocompromised Hosts Besides renal…
Fig. 5.1 Representative light microscopy showing thickened glomerular basement membranes with spikes and pinholes (arrows) on higher power. (a) PAS stain, 40×; (b) PAS 60×; (c) Silver stain 60×; (d)…
Fig. 26.1 Production and metabolism of uric acid. XO xanthine oxidase, XDH xanthine dehydrogenase, NAD nicotinamide adenine dinucleotide The best known consequence of an elevated uric acid in humans is…
