Fig. 8.1 Workflow of urine sample preparation using 96-well filter plate for shotgun proteomics. The procedures for processing both urine supernatant and pellet fractions are described. After digestion, when to clean…
Fig. 16.1 Dynamic changes in ADR-treated rats. Urinary protein to creatinine ratios in six phases of ADR-treated rats. The data are expressed as the mean ± standard deviation (n =…
Accession Max fold change in urine Change tendency in urine Max fold change in plasma Change tendency in plasma Description ITIH3_RAT 2.5 up N Inter-alpha-trypsin inhibitor heavy chain H3 CO4_RAT…
GSTP1 RASSF2 Urine (%) Plasma (%) Urine (%) Plasma (%) Positives (%) Young asymptomatic males 6 20 37 2 Biopsy negative 59 31 82 16 All stages PCa 81…
Fig. 18.1 Kidney function analysis by black box method By comparing these modified kidney input and output proteomes, this work first aims to find which proteins are blocked or permitted to…
© Springer Science+Business Media Dordrecht 2015Youhe Gao (ed.)Urine Proteomics in Kidney Disease Biomarker DiscoveryAdvances in Experimental Medicine and Biology84510.1007/978-94-017-9523-4_7 7. Applications of Peptide Retention Time in Proteomic Data Analysis Chen Shao1 (1) National Key Laboratory…
Software #PSMs(peptide spectrum match) #Peptides #Proteins Whole urine MODa 39,144 6,194 1,994 PEAKS 6 47,857 9,878 1,606a PTMs MODa 7,100 1,602 734 PEAKS 6 20,329 3,891 1,578 In vivo…
© Springer Science+Business Media Dordrecht 2015Youhe Gao (ed.)Urine Proteomics in Kidney Disease Biomarker DiscoveryAdvances in Experimental Medicine and Biology84510.1007/978-94-017-9523-4_4 4. Human Urine Proteome: A Powerful Source for Clinical Research Lili Zou1 and Wei Sun1 (1) Core…
Urinary biomarkers Localization in the kidneys Function in the kidneys Level in the urine from children with UPJO TGF-β1 Renal tubular epithelial cells, macrophages, and interstitial fibroblasts The main modulator…
12. Sun W, Chen Y, Li F, Zhang L, Yang R, Zhang Z, Zheng D, Gao Y (2009) Dynamic urinary proteomic analysis reveals stable proteins to be potential biomarkers. Proteomics—Clin…
