Human Polyomavirus (HPyV) and Organ Transplantation
Screening test Sensitivity (%) Specificity (%) PPV (%) NPV (%) BK viremiaa 100 96 50 100 BK viruriab 100 92 31 100 Decoy cellsc 25 84 5 97 Urinary capsid…
Delayed Graft Function and Kidney Transplantation
Acute tubular necrosis Urological/surgical complications • Urinary leak • Lymphocele • Ureteral obstruction • Catheter obstruction • Bleeding/hematoma Vascular causes • Hypovolemia/hypoperfusion • CNI toxicity (vasoconstriction) • Thrombosis of the…
Malignancies After Transplantation and Posttransplant Lymphoproliferative Disorder
Modifiable risk factors 1. Smoking 2. Sun exposure 3. Geographical location 4. Immunosuppressive drug therapy Non–modifiable risk factors 1. Age 2. Male gender 3. White ethnicity 4. Genetic disposition 5….
Dyslipidemia After Kidney Transplantation
Study n Age (years) Cholesterol > 200 mg/dL (%) LDL > 100 mg/dL (%) HDL < 40 mg/dL (%) TG mean (mg/dL) Moore et al. [26] 214 44.7 90 97 48 195 Aakhus et al. [27]…
Risks of Pregnancy in Renal Transplant Recipients
Matthew R. Weir and Edgar V. Lerma (eds.)Kidney Transplantation2014Practical Guide to Management10.1007/978-1-4939-0342-9_17 © Springer Science+Business Media New York 2014 17. Risks of Pregnancy in Renal Transplant Recipients Dianne B. McKay1 and Michelle A. Josephson2 (1) Department of Medicine-Nephrology, University…
Psychosocial Issues in Renal Transplantation
Matthew R. Weir and Edgar V. Lerma (eds.)Kidney Transplantation2014Practical Guide to Management10.1007/978-1-4939-0342-9_16 © Springer Science+Business Media New York 2014 16. Psychosocial Issues in Renal Transplantation Charles Cangro1 (1) University of Maryland School of Medicine, 22 S….
Approach to the Highly Sensitized Patient
Fig. 5.1 University of Maryland alloantibody removal protocol for live donor kidney recipients who have a positive crossmatch with their donor Fig. 5.2 Graft survival in positive crossmatch cases compared…
Preoperative Cardiovascular Evaluation and Management
Topic Recommendation Evidence grading Clinical assessment for active cardiac conditions • A thorough history and physical examination are recommended to identify active cardiac conditions before kidney transplantation Class I, Level…
Mechanisms of Immunosuppressive Drugs
Drug Description Mechanism of action Use in induction Use in rejection Use in maintenance Adverse effects Polyclonal antithymocyte globulin [rabbit] (Thymoglobulin®) Polyclonal IgG from rabbits immunized with human thymocytes Blocks…
Ethical Issues and Transplant Tourism
Matthew R. Weir and Edgar V. Lerma (eds.)Kidney Transplantation2014Practical Guide to Management10.1007/978-1-4939-0342-9_7 © Springer Science+Business Media New York 2014 7. Ethical Issues and Transplant Tourism Dominique E. Martin1 and Francis L. Delmonico2 (1) Centre for Health and Society, School…
