Fig. 7.1 Open retropubic radical prostatectomy: Incision of the prostatic apex Fig. 7.2 Prostatic bed after removal of the prostate 7.3 Radical Prostatectomy: Oncological Results Today there are several consolidated…
Risk classification Stage PSA Gleason Low risk T1-2a ≤10 ng/ml ≤6 Intermediated risk T2b >10 and ≤ 20 ng/ml 7 High risk T2c-3a >20 ng/ml ≥ 8 This system uses PSA level, Gleason grade, and…
Fig. 6.1 MR images of a 63-year-old patient with prostate-specific antigen (PSA) progression from 3.8 ng/mL (2012) to 4.9 ng/mL (2013). (a) High-resolution axial T2-weighted fast spin-echo image showing a focal hypointense…
Fig. 10.1 Proposed spiral model for prostate cancer progression by Logothetis [8] According to this model, the transition from endocrine to paracrine-driven prostate cancer is associated with a number of…
Parameter Value Age (years) 67.6 ± 8.5 (69), 46–76 Total PSA (ng/ml) 6.9 ± 23.2 (3.5), 0.003–146.0 Familiarity 24 (16.3) Gleason score ≤7(3 + 4) 115 (78) ≥7(4 + 3) 32 (22) Staging Localised 95 (65) Locally advanced…
Fig. 8.1 Choline PET/CT images of a 69-year-old patient with biochemical recurrence (PSA serum level 2.3 ng/ml) after radical prostatectomy for prostate cancer. (a) Axial coronal fused PET/CT image showing an…
De Leval [31] TAP 22 [28] TULP [32] FINN Prostate [34] SEUG 9401 [33] NCT 3653 [29] SWOG 9346 [30] SEUG 9901 [37] Number of cases 68 173 193…
1 PC is a very complex disease, involving diagnostic and therapeutic multidisciplinary decisions 2 Optimal and well-balanced information for PC cases requires a shift from a monodisciplinary to a synergic…
Fig. 1.1 An example of multidisciplinary team approach References 1. Gouveia J, Voleman MP, Haward R et al (2008) Improving cancer control in the European Union: conclusions from the Lisbon…
(phi) between patients with or without PCa in the tPSA range between 2.0 and 10 ng/ml. In an univariate accuracy analysis, %[−2]proPSA (AUC: 75.7 %) and phi (AUC: 75.6 %) were the most…
