Management of Anal Cancer
Description Treatment Special considerations Anal Intraepithelial Neoplasia (AIN) Dysplasia of squamous cells of the anal margin/canal; precursor lesion of SCC Surveillance for low-grade lesions Common in HIV + HIV…
Treatment of Endometrial Cancer
Fig. 30.1 Overall survival rates for patients treated with or without adjuvant pelvic radiation therapy for low-intermediate-risk or high-intermediate-risk endometrial cancer on Gynecologic Oncology Group trial GOG-99 (Reprinted from Keys…
Treatment of Rectal Cancer with Synchronous Liver Metastasis
Fig. 55.1 Treatment algorithm As is evidenced by the NCCN guidelines for the treatment of rectal cancer with resectable liver metastasis, there is no defined algorithm for the initial treatment…
Transanal Approaches to Rectal Cancer Surgery
Fig 47.1 TEMS rectoscope with the binocular eye-piece and the instruments in the appropriate ports Procedure The procedure is performed under general anesthetic with full muscle relaxation, as for abdominal…
Neoadjuvant Chemotherapy in the Management of Cervical Carcinoma
Fig. 35.1 Overall survival comparison for NACT in surgical setting from NACCMA Collaboration meta-analysis (From Tierney et al. [13]; used with permission from Elsevier) In 2007 the Gynecologic Oncology Group…
Management of Advanced Endometrial Cancer and Inhibitors of the PI3K/AKT/mTOR Pathway
Molecular lesion Type I (%) Type II (%) References PIK3CA Mutation 30 20 [20, 81–83, 122] Amplification 2–14 46 [42, 122] KRAS mutation 11–26 2 [119, 123, 124] AKT mutation…
Perioperative Care for Patients Undergoing Major Pelvic Operations
Fig. 44.1 Main elements of the ERAS protocol (Reprinted from Fearon et al. [59]; with permission from Elsevier) Fig. 44.2 Complications within an eras program. Forest plot of comparison: ERAS…
Orthotopic Bladder Substitution
Sphere T = PR/2 Cylinder T = PR T wall tension (resistance to internal vessel pressure), P internal pressure, R radius Camey and LeDuc illustrated this concept in comparing their initial orthotopic diversions. Their…
Open Surgical Management of Rectal Cancer
Fig. 49.1 Holy plane of TME dissection Partial Mesorectal Excision (High Anterior Resection and Mesorectal Transection) Upper rectal tumors (12–15 cm from the anal verge) may not require TME and…
Improving Multidisciplinary Team Working in Pelvic Oncology
Fig. 1.1 The systems approach to surgical performance (Adapted from Undre et al. [6]) The evidence for decision-making in MDT meetings covers many different aspects of the MDT meeting across…
