Pt population Intervention Comparator Outcome studied Pts with AIN 3 HRA Clinical followup Cancer prevention, cost Introduction Anal squamous cell carcinoma (ASCC) is an uncommon malignancy caused by infection with…
Patient population (P) Intervention (I) Comparator (C) Outcome studied (O) HIV pts with abnormal pap smear High resolution anoscopy (HRA) Clinical follow-up Cancer prevention, cost Results Screening HIV-infected MSM with…
Patients Intervention Comparator Outcomes Locally recurrent rectal cancer Reoperation Non-operative Palliation Cure Survival Morbidity Mortality Quality of life Results Suspicion of recurrence should prompt evaluation with imaging to assess anatomy,…
Pt population Intervention Comparator Outcomes studied Pts after LAR Proximal diversion No diversion Leak rate, consequences Introduction The standard of care for rectal cancers has evolved over recent years to…
Fig. 2.1 The GRADE process for developing recommendations (Adapted from Guyatt et al. [2]) Once a literature review is complete, each individual study must be vetted for its relevance to…
Patient population Intervention Comparator Outcomes Patients with complete response after neoadjuvant treatment of rectal cancer Non-operative management Surgery (TME) Cancer recurrence, morbidity, disease-free survival, overall survival Introduction Surgical excision of…
Patient population Intervention Comparators Outcomes Patient with T2N0 rectal cancer Local excision with chemoradiation Radical resection Chemoradiation alone Oncologic outcomes Functional outcomes Search Strategy A literature search was conducted including…
P (patients) I (intervention) C (comparator) O (outcomes) Patients with T1 rectal cancer Local excision Radical resection Oncologic outcomes, quality of life A literature search in Pubmed, Embase, and Scopus…
Pt population Intervention Comparators Outcomes studied Pts with stage 2 colon cancer Chemo Observation Disease free survival, overall survival I searched the PubMed data base using the following MeSH terms:…
P (patients) I (intervention) C (comparator) O (outcomes) Patients with obstructing colorectal cancer Surgery Self expanding metallic stents Technical success, morbidity, bridging to surgery, oncologic outcomes, survival Methods: Search Strategy…
