Development of the Enteric Neuromuscular System
Fig. 2.1 Development of enteric nervous system, smooth muscle and interstitial cells of Cajal within the developing human gut. (a) At week 11 of development, αSMA-staining (green) is apparent in…
Cyclic Vomiting Syndrome: Comorbidities and Treatment
Functional dyspepsia Functional nausea (pediatric Rome IV criteria) Functional vomiting Cyclic vomiting syndrome Rumination syndrome Aerophagia Definition Earlier clinical diagnosis has been facilitated by the recently defined consensus diagnostic criteria…
Irritable Bowel Syndrome
Rome IV. Diagnostic criteria a for irritable bowel syndrome Must include all of the following 1. Abdominal pain at least 4 days per month over at least 2 months associated with…
Functional Dyspepsia
Must include 1 or more of the following bothersome symptoms at least 4 days per month 1. Postprandial fullness 2. Early satiation 3. Epigastric pain or burning not associated with defecation 4. After appropriate…
Infant Regurgitation and Pediatric Gastroesophageal Reflux Disease
Symptoms Recurrent regurgitation with/without vomiting Weight loss or poor weight gain Irritability in infants Ruminative behavior Heartburn or chest pain Hematemesis Dysphagia, odynophagia Wheezing Stridor Cough Hoarseness Signs Esophagitis Esophageal…
Gastric Function After Fundoplication
© Springer International Publishing Switzerland 2017Christophe Faure, Nikhil Thapar and Carlo Di Lorenzo (eds.)Pediatric Neurogastroenterology10.1007/978-3-319-43268-7_31 31. Gastric Function After Fundoplication Samuel Nurko1 (1) Center for Motility and Functional Gastrointestinal Disorders, Children’s Hospital Boston, 300 Longwood Ave, Boston,…
Esophageal Atresia
Fig. 28.1 High-resolution esophageal manometry tracings recorded in patients with esophageal atresia. Aperistalsis pattern (a); distal (weak) contraction patterns (b, c). (d) A liquid swallow studied by high resolution/impedance in…
Motility Problems in Developmental Disorders: Cerebral Palsy, Down Syndrome, Williams Syndrome, Autism, Turner’s Syndrome, Noonan’s Syndrome, Rett Syndrome, and Prader-Willi Syndrome
Fig. 26.1 Examples of high-resolution esophageal manometry tracings in a control subject (a) and in two patients (b, c) affected by cerebral palsy. Note in (a) a normal esophageal tracing,…
Familial Dysautonomia and Mitochondrial Disorders
© Springer International Publishing Switzerland 2017Christophe Faure, Nikhil Thapar and Carlo Di Lorenzo (eds.)Pediatric Neurogastroenterology10.1007/978-3-319-43268-7_27 27. Familial Dysautonomia and Mitochondrial Disorders Massimo Martinelli1 and Annamaria Staiano1 (1) Department of Translational Medical Science, Section of Pediatrics, University of Naples…
Hirschsprung Disease
Short segment 74–89 % Long segment 12–22 % Total colon 4–13 % Small bowel 3–5 % Clinical Presentation HSCR is debilitating and can be fatal. Clinical presentation is highly variable…
