Abdominal Key

The recurrence of underlying disease is relatively low in cases of pediatric liver transplantation (LT) compared with adults. The underlying liver disease does not recur in biliary atresia or in…

Introduction Liver transplantation (LT) should not be considered a procedure that resolves the problem of a native liver at once but rather a “long-term care plan.” Indeed, the surgical procedure…

Introduction Solid organ transplants can be associated with a variety of hematologic abnormalities ranging from minor to life-threatening. When they occur, they may lead to prolonged admissions, reduced physical capacity,…

Immunological Mechanisms of Rejection Transplantation of an allograft induces a formidable immunological response by the recipient designed to destroy the foreign organ efficiently and quickly. Successfully controlling this complex multifaceted…

Introduction Pediatric liver transplantation (LT) has expanded since 1980 because of the broad utilization of segmental grafts including split, living donor, and, occasionally, also reduced grafts. This currently allows achievement…

Introduction Pediatric liver transplantation (PLT) sits at the pinnacle of pediatric surgical endeavors. In the early years, long-term survival rates after PLT were 11% to 39% and, since then, have…

Introduction Although the liver is known to be a somewhat immunotolerant organ, pediatric liver transplantation (LT) would not have reached current success without efficient immunosuppressive drugs. Standard protocols include calcineurin…

Introduction Anesthesia for pediatric liver transplantation is complex, diverse, and challenging. The indications for transplantation and the physiology of children vary from the adult population, making the pediatric service unique….

Introduction Intestinal transplantation (ITx) was first attempted in the 1970s in children with intestinal failure (IF) for whom intravenous nutrition was not available. The early efforts did not meet with…

Liver-Heart Indication Combined heart and liver transplantation (CHLT) is still an evolving procedure, representing only 0.3% of all cardiac transplantation in a Unified Network for Organ Sharing (UNOS) database study…