Management of Colonic Ischemia
Introduction Intestinal ischemia produces a spectrum of diseases affecting the gastrointestinal tract. These syndromes, which can be acute or chronic, can affect the upper abdominal viscera, as well as the…
Management of Metastatic Colorectal Cancer
Acknowledgments Dr. Khorana acknowledges research support from the Sondra and Stephen Hardis Endowed Chair in Oncology Research, the Scott Hamilton CARES Initiative, the Porter Family Fund for Biliary Genomics Research,…
Nonepithelial Colorectal Tumors
Introduction Nonepithelial tumors of the colon and rectum are rare and represent fewer than 1% of all neoplasms of the colon and the rectum. They can be categorized as benign…
Colorectal Metastases to the Lung
Introduction Colorectal carcinoma metastasizes to the lung in 10% to 15% of patients. The decision about whether to perform surgery for a patient with lung metastasis must take into account…
Management of Colorectal Liver Metastasis
Introduction The liver is the most common site for colorectal cancer (CRC) metastases; 15% to 20% of patients present with synchronous lesions, and metachronous metastases occur in 40% to 50%…
Cancer of the Appendix and Pseudomyxoma Peritonei Syndrome
Introduction Malignant tumors of the appendix are rare, making up approximately 0.4% of all intestinal neoplasms. About 1% of all large bowel cancers arise from the appendix. The histopathology of…
Hereditary Nonpolyposis Colorectal Cancer and Lynch Syndrome
Introduction Approximately 5% of all colorectal cancers (CRCs) are associated with a hereditary syndrome, where a germline mutation in a key tumor suppressor or DNA repair gene produces a cancer…
Desmoid Disease
Introduction Desmoid disease is a benign proliferation of fibroblasts that produces a spectrum of manifestations from rapidly growing tumors to indolent nodules and flat sheets of tissue that distort surrounding…
Colonic Pseudo- obstruction (Ogilvie Syndrome)
Introduction Acute colonic pseudo-obstruction, also known as Ogilvie syndrome, is a nonmechanical, functional obstruction of the large intestine. It has become a well-known clinical entity, but in many regards it…
Management of the Malignant Polyp
Introduction Malignant polyps of the large intestine can be divided into polypoid cancers, which are largely cancerous lesions with a polypoid shape, and polyps that are mostly benign but have…
