Study Infliximab (n) Non-infliximab (n) Total (n) Odds ratio Appau et al. [8] 60 329 389 2.93 (1.63–5.27) Canedo et al. [11] 65 160 225 1.19 (0.58–2.42) Kasparek et al….
Fig. 3.1 Induction of remission with corresponding placebo rates from seminal clinical trials for each anti-TNF (note: trials had different inclusion criteria and end points and thus while presented on…
Infliximab Adalimumab Certolizumab Golimumab CT-P13 ABP501 sTNF binding Y Y Y Y Y Y mTNF binding Y Y Y Y Y Y mTNF reverse signaling Y Y ? Y…
© Springer International Publishing AG 2018Adam S. Cheifetz and Joseph D. Feuerstein (eds.)Treatment of Inflammatory Bowel Disease with Biologics https://doi.org/10.1007/978-3-319-60276-9_4 4. Anti-TNF Therapy for Treatment of Extraintestinal Manifestations of Inflammatory Bowel Disease David I. Fudman1 and Sarah N. Flier1 …
Term Definition Adverse pregnanc y outcomes Spontaneous abortion/miscarriage Induced abortion Preterm birth (delivery <37 weeks of gestation) Small for gestational age (birth weight <10th percentile for gestational age) Stillbirth Ectopic…
Anti-TNFα medication Authors, date Study summary Study population, sample size Dosing information Clinical response Clinical remission and mucosal improvement Infli ximab Rutgeerts et al. [15] Induction (ACT 1) 364 TNF-naïve…
Fig. 2.1 Estimating polyp siz e using biopsy forceps. The biopsy forceps have jaws with 2.5 mm in diameter, which open to a width of 7 mm For the successful…
Fig. 5.1 Immediate bleeding after polypectomy can be easily controlled by coagulation Fig. 5.2 (a) Active bleeding site covered with blood clots, (b) bleeding control by clipping 5.1 APC (Argon…
Category Diagnosis 1 Negative for neoplasia 2 Indefinite for neoplasia 3 Mucosal low grade neoplasia Low grade adenoma Low grade dysplasia 4 Mucosal high grade neoplasia 4–1 High grade adenoma/dysplasia…
Fig. 3.1 Classification of LSTs The size and type of LSTs are good predictors of invasive cancer, and the proportion of submucosal carcinoma increases with increasing size of flat depressed…
