Physiologic and Neural Controls of Eating
Multiple physiologic and neural systems contribute to the controls over what and how much we eat. These systems include signaling involved in the detection and signaling of nutrient availability, signals…
Is Obesity Associated with Barrett’s Esophagus and Esophageal Adenocarcinoma?
Barrett’s esophagus is a premalignant condition portending increased risk of esophageal adenocarcinoma. Given the significant morbidity and mortality of esophageal adenocarcinoma, identification of risk factors for Barrett’s esophagus and esophageal…
The Gut Microbiota
Obesity is an emerging global epidemic with profound challenges to world health care economies and societies. Traditional approaches to fighting obesity have not shown promise in promoting a decline in…
Obesity Epidemiology Worldwide
Obesity continues to be a public health concern across the globe. Obesity has a demonstrated association with health behaviors and health outcomes, such as diabetes, hypertension, and cancer. Over the…
Obesity and Gastroenterology
Octavia Pickett-Blakely, MD, MHS, Editor Linda A. Lee, MD, Editor Overweight and obesity have emerged as major threats to public health all over the world. The 2013 Burden of Disease…
Fecal Microbiota Transplantation
Fecal microbiota transplantation (FMT) is the transfer of stool from a healthy donor into the colon of a patient whose disease is a result of an altered microbiome, with the…
Gut Microbiota and Complications of Liver Disease
Chronic liver disease, cirrhosis, and its complications are epidemic worldwide. Most complications are mediated through a dysfunctional gut-liver axis. New techniques have made culture-independent analysis of the gut microbiome widespread….
The Gut Microbiota in Inflammatory Bowel Disease
Genes, bacteria, and immunity contribute to the pathogenesis of inflammatory bowel disease. Most genetic risk relates to defective sensing of microbes and their metabolites or defective regulation of the host…
The Esophageal and Gastric Microbiome in Health and Disease
The esophagus and stomach are host to their own population of bacteria, which differs in health and disease. Helicobacter pylori uniquely colonizes only gastric mucosa, but an increasing number of…
Small Intestinal Bacterial Overgrowth and Other Intestinal Disorders
Gut microbiota is the largest organ of the human body. Although growth of bacteria more than 10 5 colony forming unit (CFU) per milliliter in culture of upper gut aspirate…
