Drugs and liver disease
Chapter 41 DRUGS AND LIVER DISEASE KEY POINTS • Drugs have become the leading cause of acute liver failure in Western countries. • The liver plays a central role in…
Acute liver failure
Chapter 47 ACUTE LIVER FAILURE KEY POINTS • Acute liver failure (ALF) is defined as the rapid development of coagulopathy and mental status changes in a patient with deteriorating liver…
Mass in the liver
Chapter 44 MASS IN THE LIVER KEY POINTS • Widespread use of modern imaging modalities has resulted in frequent identification of incidental focal liver masses/nodules. • Advances in imaging techniques…
Occult gastrointestinal bleeding and iron deficiency anaemia
Chapter 23 OCCULT GASTROINTESTINAL BLEEDING AND IRON DEFICIENCY ANAEMIA KEY POINTS • The source of gastrointestinal bleeding is undetected in up to 30% of patients in whom adequate and timely…
Alcoholic liver disease
Chapter 40 ALCOHOLIC LIVER DISEASE KEY POINTS • Alcohol is one of the most common causes of liver disease—alcoholic liver disease (ALD). • The clinical and pathological spectrum of ALD…
Granulomatous liver disease
Chapter 43 GRANULOMATOUS LIVER DISEASE KEY POINTS • The hallmark of granulomatous liver inflammation is the epithelioid granuloma. • The aetiology is multifactorial: infections (e.g. tuberculosis), sarcoidosis, primary biliary cirrhosis,…
Obesity and abnormal liver function tests
Chapter 39 OBESITY AND ABNORMAL LIVER FUNCTION TESTS KEY POINTS • Non-alcoholic fatty liver disease (NAFLD) is the most common cause of abnormal liver function tests in the Western world….
Chronic non-viral hepatitis
Chapter 38 CHRONIC NON-VIRAL HEPATITIS KEY POINTS • Chronic non-viral hepatitis is a clinicopathologic liver syndrome most commonly due to autoimmune hepatitis. • Other causes include cryptogenic hepatitis, and drug…
Malabsorptive disorders and coeliac disease
Chapter 11 MALABSORPTIVE DISORDERS AND COELIAC DISEASE KEY POINTS • Malabsorption may present with weight loss, bloating, diarrhoea and specific vitamin and nutrient deficiencies. • Identification of the underlying cause…
Suspected iron overload or high serum ferritin
Chapter 37 SUSPECTED IRON OVERLOAD OR HIGH SERUM FERRITIN KEY POINTS • Iron is a component of a number of essential proteins. • Iron surplus to body needs is stored…
