Acute liver failure

Chapter 47 ACUTE LIVER FAILURE






CAUSES OF ACUTE LIVER FAILURE


Acute liver failure represents a syndrome that is the final common pathway for a variety of liver insults. A cause for ALF can be established in approximately 60%–80% of cases. There is a marked worldwide variation in the relative incidence of the various underlying causes. For example, in Australia, the UK and the USA, medications (e.g. paracetamol) and idiosyncratic drug reactions are the most commonly identified aetiologies. In other parts of the world, including Asia, acute viral hepatitis is a leading cause of ALF.







CLINICAL FEATURES AND MAJOR COMPLICATIONS


The clinical features of ALF result from reduced hepatocellular function and from complications involving other organs. Non-specific symptoms such as nausea, vomiting and malaise are common initially, closely followed by the onset of jaundice.


Mar 29, 2017 | Posted by in GASTROENTEROLOGY | Comments Off on Acute liver failure
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