Optimization of Prostate Biopsy
A 12-core systematic biopsy that incorporates apical and far-lateral cores in the template distribution allows maximal cancer detection and avoidance of a repeat biopsy while minimizing the detection of insignificant…
Decision Making and Prostate Cancer Screening
This article presents an overview of the challenges that men encounter in making decisions about prostate cancer screening, including complex affective and cognitive factors and controversies in the interpretation of…
Emerging PSA-Based Tests to Improve Screening
Key points • Using prostate-specific antigen (PSA) derivatives and additional kallikrein markers for prostate cancer diagnosis can improve the current performance characteristics of the PSA test alone. • An improved…
The Politics of Prostate Cancer Screening
The controversial recent recommendation by the United States Preventive Services Task Force (USPSTF) against prostate-specific antigen (PSA) screening for early-stage prostate cancer has caused much debate. Whereas USPSTF recommendations against…
International Perspectives on Screening
The estimated population of the world in 2008 was 6.75 billion people, increasing by around 79 million people each year. The world population is aging. In 1970, the world median…
Evolution and Immediate Future of US Screening Guidelines
Although observational studies and simulation models have shed some interesting light on many of the uncertainties surrounding prostate cancer screening, well-done clinical trials provide the best evidence on screening among…
What Do the Screening Trials Really Tell Us and Where Do We Go From Here?
Publication of apparently conflicting results from 2 large trials of prostate cancer screening has intensified the debate about prostate-specific antigen (PSA) testing and has led to a recommendation against screening…
Early Detection of Prostate Cancer
Stacy Loeb, MD, MSc, Editor Matthew R. Cooperberg, MD, MPH, Editor Although prostate cancer remains the second leading cause of cancer death among men in the United States, in the…
Early Detection of Prostate Cancer
Samir S. Taneja, MD, Consulting Editor During the period of my career in Urology, we have come full circle in the arena of prostate cancer. As a student in the…
Urodynamics in the Evaluation of Female LUTS
Urodynamics remains the test of choice to evaluate lower urinary tract symptoms in men and women. Best practices recommend that urodynamics be applied to answer a specific urodynamic question. Recent…
