The Intraoperative and Perioperative Management of Kidney Transplantation

Oct 6, 2016 by in GASTROENTEROLOGY Comments Off on The Intraoperative and Perioperative Management of Kidney Transplantation

22. Costa NA, Kshirsagar AV, Wang L, Detwiler RK, Brookhart MA. Pretransplantation erythropoiesis-stimulating agent hyporesponsiveness is associated with increased kidney allograft failure and mortality. Transplantation. 2013;96(9):807–13.PubMedCentralCrossRefPubMed 23. Dauru M, et…

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Living Donor Nephrectomy

Oct 6, 2016 by in GASTROENTEROLOGY Comments Off on Living Donor Nephrectomy

Fig. 18.1 Vein graft for living kidney transplantation and back table of an artery graft for living kidney transplantation 18.2.2 Retroperitoneal The donor is placed in the lateral decubitus position…

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Live Donor Evaluation

Oct 6, 2016 by in GASTROENTEROLOGY Comments Off on Live Donor Evaluation

History and examination Instrumental investigations Microbiological screening Laboratory investigations Immunological investigations Family history Chest radiograph HBV Blood count and coagulation Blood group Pathological history Electrocardiogram HCV Urea, creatinine, serum uric…

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Indications and Timing

Oct 6, 2016 by in GASTROENTEROLOGY Comments Off on Indications and Timing

Fig. 15.1 Natural history of renal disease To determine the timing, i.e., when to proceed to transplantation, a distinction must be made between theory and practice. In theory, transplant should…

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Postoperative Technical Complications

Oct 6, 2016 by in GASTROENTEROLOGY Comments Off on Postoperative Technical Complications

Fig. 12.1 Percutaneous transhepatic cholangiography showing typical findings of intrahepatic biliary dilatation and stenosis, “cast syndrome,” due to posttransplant hepatic thrombosis. Early surgical revascularization was performed, but the patient required…

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Anaesthetic and Perioperative Management for Liver Transplantation

Oct 6, 2016 by in GASTROENTEROLOGY Comments Off on Anaesthetic and Perioperative Management for Liver Transplantation

Hepatic Renal electrolyte glucose Cardiovascular Pulmonary Neurologic Haematologic Decreased metabolic function Acute kidney injury Vasodilated state Aspiration risk Hepatic encephalopathy Bleeding and thrombosis Decreased gluconeogenesis Hepatorenal syndrome Hyperdynamic cardiac function…

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Liver Procurement

Oct 6, 2016 by in GASTROENTEROLOGY Comments Off on Liver Procurement

Category Description I Dead on arrival: corneas, heart valves, skin, bone, etc., can be recovered since there are no immediate time constraints to minimize tissue injury and there is no…

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Infection Complications After Abdominal Organ Transplantation

Oct 6, 2016 by in GASTROENTEROLOGY Comments Off on Infection Complications After Abdominal Organ Transplantation

Greater infectious risk  Critical illness entering transplantation  Prior colonization with antimicrobial-resistant pathogens  Induction therapy – lymphocyte depletion  High-dose corticosteroids  Plasmapheresis (not well studied)  High rejection risk (HLA mismatch desensitization)  Early…

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Transplantation Immunology

Oct 6, 2016 by in GASTROENTEROLOGY Comments Off on Transplantation Immunology

Fig. 1.1 Structure of mTOR inhibitors, everolimus (left), and sirolimus (right). Everolimus differs from sirolimus due to the addition of a 2-hydroxyethyl group at C40 Table 1.1 mTOR inhibitors –…

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Indications for Liver Transplantation

Oct 6, 2016 by in GASTROENTEROLOGY Comments Off on Indications for Liver Transplantation

Acetaminophen-induced ALF Nonacetaminophen ALF Arterial pH <7.3 irrespective of grade of encephalopathy or INR >6.5 (PT >100 s), irrespective of grade of encephalopathy PT >100 s Or any 3 of…

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