Fig. 18.1 Kidney function analysis by black box method By comparing these modified kidney input and output proteomes, this work first aims to find which proteins are blocked or permitted to…
GSTP1 RASSF2 Urine (%) Plasma (%) Urine (%) Plasma (%) Positives (%) Young asymptomatic males 6 20 37 2 Biopsy negative 59 31 82 16 All stages PCa 81…
© Springer Science+Business Media Dordrecht 2015Youhe Gao (ed.)Urine Proteomics in Kidney Disease Biomarker DiscoveryAdvances in Experimental Medicine and Biology84510.1007/978-94-017-9523-4_4 4. Human Urine Proteome: A Powerful Source for Clinical Research Lili Zou1 and Wei Sun1 (1) Core…
Software #PSMs(peptide spectrum match) #Peptides #Proteins Whole urine MODa 39,144 6,194 1,994 PEAKS 6 47,857 9,878 1,606a PTMs MODa 7,100 1,602 734 PEAKS 6 20,329 3,891 1,578 In vivo…
© Springer Science+Business Media Dordrecht 2015Youhe Gao (ed.)Urine Proteomics in Kidney Disease Biomarker DiscoveryAdvances in Experimental Medicine and Biology84510.1007/978-94-017-9523-4_7 7. Applications of Peptide Retention Time in Proteomic Data Analysis Chen Shao1 (1) National Key Laboratory…
12. Sun W, Chen Y, Li F, Zhang L, Yang R, Zhang Z, Zheng D, Gao Y (2009) Dynamic urinary proteomic analysis reveals stable proteins to be potential biomarkers. Proteomics—Clin…
Urinary biomarkers Localization in the kidneys Function in the kidneys Level in the urine from children with UPJO TGF-β1 Renal tubular epithelial cells, macrophages, and interstitial fibroblasts The main modulator…
Authors Type of disease Participants Method Identified proteins Rossing et al. [38] DN 305 individuals CE-MS A model that included 65 regulated genes correctly identified diabetic nephropathy with 97 % sensitivity…
© Springer Science+Business Media Dordrecht 2015Youhe Gao (ed.)Urine Proteomics in Kidney Disease Biomarker DiscoveryAdvances in Experimental Medicine and Biology84510.1007/978-94-017-9523-4_14 14. Applications of Urinary Proteomics in Renal Disease Research Using Animal Models Yang Lv1, Guangyan Cai1 and…
