Target of investigation Available tests Antisperm antibodies Mixed agglutination reaction (MAR) test Direct immunobeads binding test (direct IBT) Fertilization defects Hemizona assay Sperm–zona binding ratio test Hyperactivation (HA) motility Acrosome…
Fig. 28.1 Human ovarian steroidogenesis. The starting point for steroid biosynthesis is the conversion of cholesterol in pregnenolone by P450scc. One route of pregnenolone metabolism is the delta-5 pathway (…
Parameter Unexplained male infertility Idiopathic male infertility Semen analysis [1, 2, 6] Normal Abnormal History, physical exam, and endocrine assessment [2, 3, 14] Normal Normal Female factor infertility [2, 6]…
Fig. 18.1 Normal fallopian tube. Salpingoscopy reveals normal-looking mucosa in the ampullary (a) and infundibular (b) regions. A thin section of the ampulla (c) shows normal ciliated endosalpinx. Electron microscopy…
Reference Protocol Success of pregnancy Shulman et al. [50] Male patients receive 96 mg/day methylprednisolone from days 21 to 28 of the female menstrual cycle 44 % pregnancy rate in first 12…
Fig. 25.1 Relationship to age. a Pregnancy rate ( horizontal bars) and multiple implantation rates ( lines) per cycle. b Number of follicles > 12 mm ( horizontal bars) implants per…
Fig. 5.1 The human spermatozoa, testis, and epididymis. To the left is a mature human spermatozoon showing the components that make up the head, midpiece and tail sections. To the right…
Factor Incidence (%) Male 40 Ovulatory dysfunction 35 Uterine-tubal 25 Peritoneal/endometriosis 15 Cervical mucus 10 Under developed endometrium 10 Table 20.2 Infertility factors in 100 couples referred to the fertility…
49. Coward K, Kubota H, Hibbit O, McIlhinney J, Kohri K, Parrington J. Expression of a fluorescent recombinant form of sperm protein phospholipase C zeta in mouse epididymal sperm by…
Outcome measure OR or RR (95 % CI) IVF versus expectant management (CPR) OR = 3.24 (95 % CI = 1.07–9.80)* IVF versus expectant management (LBR) OR = 22.00 (95…
