The past decade has led to marked improvements in our understanding regarding the pathogenesis and risk of progression of Barrett’s esophagus (BE), enhanced imaging technology to improve dysplasia detection, and…
Esophageal adenocarcinoma is increasing in incidence. The main risk factor is the premalignant condition of Barrett’s esophagus. There is great interest in chemoprevention to prevent or slow malignant transformation. There…
Advances in the development of endoscopic therapies for Barrett’s esophagus have resulted in the emergence of an important paradigm shift for management of early neoplasia and represent an opportunity to…
Gastroesophageal reflux disease (GERD) is a highly prevalent disease. Population studies have demonstrated that a significant proportion of individuals weekly experience GERD symptoms. Barrett’s esophagus (BE), defined by the presence…
Recent developments in endoscopic therapeutic options for Barrett’s esophagus (BE) early neoplasia have resulted in a dramatic paradigm shift in its clinical management. With multiple endoscopic choices available, it is…
Studies in the last several years have consistently shown radiofrequency ablation (RFA) to be effective, safe, and well tolerated in the treatment of nondysplastic and dysplastic Barrett’s esophagus (BE). The…
Cryotherapy is a noncontact ablation method that has long been used clinically in the treatment of a wide variety of malignant and premalignant diseases. The relative ease of use and…
Endoscopic resection (ER) has become the most important endoscopic treatment method of early cancers of the upper GI tract. ER serves as a therapeutic but also as a diagnostic tool…
Photodynamic therapy (PDT) is a photochemical process that uses a photosensitizer drug activated by laser light to produce mucosal ablation. Porfimer sodium PDT has proved long-term efficacy and durability in the…
Enhanced visualization techniques are available for Barrett’s esophagus and have promise in the detection of dysplasia and cancer. Several of these techniques, such as narrow band imaging and chromoendoscopy, are…
