Traditionally, endoscopic mucosal resection and surgery were the only available treatments for large colorectal tumors, even for those detected at an early stage. The endoscopic submucosal dissection (ESD) technique, which…
Molecular imaging is a rapidly growing new discipline in gastrointestinal endoscopy that involves the development of novel imaging probes and instruments to visualize the molecular expression pattern of mucosa in…
Colorectal cancer is a heterogeneous disease arising through multiple possible pathways. Elucidating the genetic factors controlling molecular phenotype, morphology, histology, and prognosis of different tumor types continues to be a…
Until recently, 2 major forms of colorectal polyp were recognized: the adenoma and the hyperplastic polyp. Adenomas were known to represent a precursor to colorectal cancer, whereas hyperplastic polyps were…
Computed tomographic colonography (CTC) has been reported to be as effective as optical colonoscopy in the detection of significant adenomas. However, there are widely conflicting performance data in relation to…
The incidence of colorectal cancer associated with ulcerative colitis (UC) increases with time. It is imperative to identify dysplasia-associated lesions or masses (DALM) and non-polypoid colorectal neoplasms (NP-CRN) to reduce the…
This article describes the submucosal injection technique applied in the endoscopic resection of non-polypoid colorectal neoplasms, with an emphasis on a particular technique, the dynamic submucosal injection technique. Submucosal injection…
Endoscopic mucosal resection (EMR) is preferred to standard polypectomy for the resection of non-polypoid lesions because these lesions can be technically difficult to capture with a snare; furthermore, without submucosal…
Colonoscopy, the most sensitive test used to detect advanced adenoma and cancer, has been shown to prevent colorectal cancer (CRC) when combined with polypectomy. CRC remains the third most commonly…
Although of lower prevalence compared with polypoid neoplasms, the non-polypoid neoplasms, especially the depressed type, are important to diagnose because they belong to a distinct biologically aggressive subset, given the…
