Fig. 2.1 Two-layers of anti-inflammatory mucosal immune defense preserving the integrity of the intestinal epithelial barrier. Depiction of the homeostatic mechanisms: (1) Immune exclusion to control epithelial colonization of microorganisms…
• Nail clubbing and palmar erythema • Erythema nodosum • Aphthous ulcers and glossitis • Thrombophlebitis • Perianal fissures, fistulae and abscesses—more severe in Crohn disease than ulcerative colitis • Genital or orofacial Crohn disease • Peri-stomal…
Fig. 19.1 Example of dose reduction at lower kV in a 43-year-old female with prior right hemicolectomy. CTDIvol lowered from 24 mGy (routine protocol) to 10 mGy after kV selection…
Sequence Plane Number of sections Section thickness (mm) Field of view (mm) Advantages Limitations HASTE/SSFSE Coronal 1 50 512 × 512 Minimal susceptibility artefact Prone to flow artefacts SSFP (True-FISP/FIESTA)…
Fig. 22.1 Architectural distortion is a feature of chronic injury. (a) Normal colonic mucosa displays evenly spaced non-branched crypts that line up along the muscularis mucosa. Lamina propria contains sparse…
Fig. 20.1 Fig. 20.2 Fig. 20.3 First layer: hyperechoic, interface between the lumen and superficial mucosa. Second layer: hypoechoic, interface between the deep and superficial mucosa. Third layer: hyperechoic, interface…
Fig. 55.1 From Zeider H, Amor B. The Assessment in Spondyloarthritis International Society (ASAS) classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general: the spondyloarthritis concept in progress. Ann…
Fig. 17.1 Enhanced endoscopic technologies to improve the three essential steps to final diagnosis Recognition of lesions in the gut can be improved using better scopes, which have better imaging…
Fig. 44.1 Clinical response (above) and remission (below) rates for golimumab induction therapy in PURSUIT-SC Fig. 44.2 Rates of mucosal healing (Mayo 1 or 0, left panel) and inactive mucosal…
Haplotype Significance in PSC B8-TNF*2-DRB3*0101-DRB1*0301-DQA1*0501-DQB1*0201 Strong association with disease susceptibility DRB3*0101-DRB1*1301- DQA1*0103-DQB1*0603 Strong association with disease susceptibility DRB5*0101-DRB1*1501- DQA1*0102-DQB1*0602 Weak association with disease susceptibility DRB4*0103-DRB1*0401-DQA1*03-DQB1*0302 Strong association with protection against…
