Fig. 2.1 Fractions of circulating total testosterone SHBG can vary considerably in men, greatly affecting total testosterone levels. Because SHBG-bound testosterone is not bioavailable, relying solely on total testosterone as…
Fig. 5.1 (a–d) Total, calculated free, calculated bioavailable testosterone (T), and LH (log. transformed) levels as a function of obesity classes. Data are expressed as mean (95% confidence interval). BMI…
Fig. 7.1 Hypothalamus-pituitary-gonadal axis. (Reprinted from Zavos, P. (2009). Male Infertility. Retrieved from http://www.homefertility.com/mi.html. With permission from Prof. Dr. Panayiotis Zavos.) The onset of normal puberty varies between children, but…
Publications and clinical trials 2003–2011 Clinical trial Series Review Othera Testosterone and sexual dysfunction 15 38 46 69 Testosterone and frailty 9 4 27 2 Testosterone and well-being 5 6…
2. Maggi M, Schulman C, Quinton R, Langham S, Uhl-Hochgraeber K. The burden of testosterone deficiency syndrome in adult men: economic and quality-of-life impact. J Sex Med. 2007;4:1056–69.PubMedCrossRef 3. Davidson…
Group A: Symptoms and signs suggestive of androgen deficiency in men • Incomplete sexual development, aspermia, eunuchoid body habitus • Reduced sexual desire (libido) and activity • Decreased spontaneous erections…
Fig. 10.1 TRT market overview There are many reasons for the rapid growth of the TRT market. We have an aging population, with the number of men 65 and older…
Sensitivity (%) Specificity (%) NPV (%) PPV (%) R(+) R(−) Diag. OR TT 25.0 100 89.6 100 Infinite 0.75 Infinite FT (RIA) 33.3 96.2 90.4 57.1 8.76 0.69 12.7…
2. Spratt DI, O’Dea LSL, Schoenfeld D, Butler J, Rao PN, Crowley Jr WF. Neuroendocrine-gonadal axis in men: frequent sampling of LH, FSH, and testosterone. Am J Physiol. 1998;254:E658–66. 3….
Reliability: a description of how well repeated measurements of the same parameter, with the same instrument, agree with one another Inter-rater reliability: a description of how well measurements of the…
