Neuroendocrine Tumors Biomarkers
Fig. 5.1 Neoplastic causes of elevated Chromogranin A (CgA). CgA elevations occur in different types of NETs but are usually more pronounced in GEP-NETs (small intestinal, gastric, and pancreatic NETs)….
Sporadic Gastroenteropancreatic Neuroendocrine Tumors
Tumor Biologically active peptide Tumor sites (abdominal) Main symptoms/signs Carcinoid syndrome Serotonin, tachykinins Midgut, pancreas Diarrhea, abdominal pain, flushing Gastrinoma Gastrin Duodenum, pancreas Pain, diarrhea Insulinoma Insulin Pancreas Hypoglycemic symptoms…
Classification of Abdominal Neuroendocrine Tumors
Fig. 2.1 Histologic features of digestive neuroendocrine neoplasms as exemplified in the pancreas according to morphologic criteria for tumor grading. Well-differentiated neuroendocrine tumors of grade 1 exhibit organoid appearance featuring…
