Overall Bottom Line Routine monitoring of liver tests throughout the early and late post-transplantation period is essential in screening for allograft dysfunction. Many causes of graft dysfunction including rejection and…

Overall Bottom Line With recipients living longer after undergoing LT, it has been noted that significant causes of morbidity and mortality post-transplantation are not related to recurrent liver disease. The…

Overall Bottom Line Due to long-term immunosuppression therapy, the post-LT recipient is at risk for disease conditions (e.g. infection, malignancy) that are generally regulated by the body’s immune system. Skin…

Overall Bottom Line LT, by necessity, subjects the liver allograft to ischemia followed by reperfusion. The pattern and severity of IRI that ensues may be clinically irrelevant in the majority…

Overall Bottom Line HPS is defined by decreased arterial oxygenation due to right to left shunting in patients with liver disease in the absence of intrinsic lung disease. HPS is…

Overall Bottom Line Bleeding due to portal hypertension remains a significant cause of morbidity and mortality in cirrhotic patients. Portal hypertension can lead to bleeding from esophageal varices, gastric varices,…

Overall Bottom Line ALF is a rare disorder that occurs mostly in young adults and is associated with high mortality and resource cost. Severe hepatic injury results in rapid deterioration…

Overall Bottom Line Neonatal cholestasis is a condition characterized by the elevation of conjugated bilirubin. Infants with cholestasis often depend on the general practitioner for proper diagnosis and appropriate initial…

Overall Bottom Line There are four key components of the surgical evaluation of patients for LT based on necessity, suitability, strategy and informed consent: 1. Necessity: does this patient need…

Overall Bottom Line LDLT is a viable alternative to the liver graft supply shortage when both donor and recipient are carefully chosen and when the surgery and donor evaluation are…