48: Vascular Complications of Liver Transplantation
Overall Bottom Line A unique feature of the liver is its dual blood supply via the hepatic artery and portal vein. LT requires a minimum of three, and very frequently…
GASTROENTEROLOGY
29: Non-Cirrhotic Portal Hypertension
Overall Bottom Line Cirrhosis is the most common cause of portal hypertension. Causes of NCPH include hepatovenous or portomesenteric thrombosis, alcoholic hepatitis and sinusoidal obstruction syndrome. Atypical patterns of intrahepatic…
44: Acute Rejection
Overall Bottom Line From a clinical perspective it is very important to distinguish between “histological” and “clinically relevant” AR. The majority of AR episodes occur in the first 6 weeks…
49: Biliary Complications after Liver Transplantation
Overall Bottom Line Improvements in organ selection, procurement and preservation have dramatically reduced the incidence of biliary complications after LT. Despite standardization of surgical methods in biliary reconstruction, immunosuppression, and…
53: Recurrent Disease Post-Liver Transplantation: Autoimmune Diseases, Hepatitis B and NASH
Overall Bottom Line Autoimmune liver conditions such as AIH, PBC and PSC all recur post-LT but graft loss is uncommon. Patients with HBV do extremely well post-LT because of the…
45: Chronic Rejection
Overall Bottom Line The most frequent CR is preceded by one or more episodes of AR that are often resistant to corticosteroid therapy and require anti-lymphocyte or other rescue therapy….
50: Approach to Prophylaxis and Management of Infections after Liver Transplantation
Overall Bottom Line The prevention of bacterial, fungal and viral infections after LT is essential to successful outcomes. Early recognition of infection is essential for implementing the appropriate treatment strategy…
32: Surgery in Patients with Liver Disease
Overall Bottom Line Patients with underlying acute and chronic liver disease are at risk of morbidity and mortality after surgery. The magnitude of the risk is related to the severity…
16: Wilson Disease
Overall Bottom Line WD, also known as hepatolenticular degeneration, is a rare autosomal recessive systemic disorder caused by defective copper metabolism. It most commonly presents with isolated hepatic, neurological or…
5: Hepatitis B and D
Overall Bottom Line HBV infection is a significant global health problem. Chronic hepatitis B is a major cause of cirrhosis, fulminant hepatitis and HCC worldwide. Chronic hepatitis B is responsible…
