Introduction Many providers are often faced with the decision of selecting the best test available from their armamentarium to diagnose gastroparesis. This can be challenging with recent evidence showing poor…

Gastroparesis Background Gastroparesis is a chronic disorder characterized by delayed gastric emptying in the absence of mechanical obstruction, which results in typical symptoms of nausea, vomiting, bloating, abdominal distention, postprandial…

Abbreviations AAG Autonomic autoimmune ganglionopathy ANS Autonomic nervous system ATTR Transthyretin amyloid COMPASS composite autonomic symptom score EDS Ehlers-Danlos syndrome HIV Human Immunodeficiency Virus POTS Postural orthostatic tachycardia syndrome TTR…

Introduction Gastroparesis causes impairment in quality of life with deleterious impacts on health. Complicating our understanding of the condition is the combination of different insults which can provoke the disorder….

Introduction Gastroparesis is a disease that affects the stomach’s motility and digestion, preventing proper stomach emptying. As a complex organ, the stomach empties both solid food and liquids at different…

Gastroparesis occurs commonly as a complication of long-standing diabetes, but the in the largest group of patients no cause can be established and these are referred to as idiopathic gastroparesis…

Abbreviations Ano-1 anoctamin-1 BH4 tetrahydrobiopterin BMP-2 bone morphogenetic protein-2 BMPR BMP receptor ChAT choline acetyltransferase CSF-1 colony stimulating fator-1 CX3CR1 CX3C chemokine receptor 1 DG diabetic gastroparesis DM diabetes mellitus…

Introduction Gastric motor functions represent a complex series of regional relaxations (e.g., fundus and pylorus) and contractions (gastric body and antrum) that are regulated by circulating blood glucose and hormones…