Fig. 55.1 From Zeider H, Amor B. The Assessment in Spondyloarthritis International Society (ASAS) classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general: the spondyloarthritis concept in progress. Ann…
Fig. 17.1 Enhanced endoscopic technologies to improve the three essential steps to final diagnosis Recognition of lesions in the gut can be improved using better scopes, which have better imaging…
Fig. 44.1 Clinical response (above) and remission (below) rates for golimumab induction therapy in PURSUIT-SC Fig. 44.2 Rates of mucosal healing (Mayo 1 or 0, left panel) and inactive mucosal…
Haplotype Significance in PSC B8-TNF*2-DRB3*0101-DRB1*0301-DQA1*0501-DQB1*0201 Strong association with disease susceptibility DRB3*0101-DRB1*1301- DQA1*0103-DQB1*0603 Strong association with disease susceptibility DRB5*0101-DRB1*1501- DQA1*0102-DQB1*0602 Weak association with disease susceptibility DRB4*0103-DRB1*0401-DQA1*03-DQB1*0302 Strong association with protection against…
Diagnosis Primary basis for diagnosis Imaging evidence Collateral evidence Definitive type 1 AIP Histology Typical/indeterminate Histologically confirmed LPSP (level 1 H) Imaging Typical Any non-D level 1/level 2 Indeterminate Two…
• All patients, regardless of extent of disease at initial diagnosis, should undergo a screening colonoscopy a maximum of 8 years after onset of symptoms, with multiple biopsy obtained throughout the…
Fig. 48.1 Inflammation (left panel) and fibrostenosis (right panel) The progression from early to late disease is accompanied by a change in mucosal cytokine profiles. Early CD is characterized by…
Fig. 50.1 CT image of isolated small bowel Crohn’s disease (arrows). This image clearly demonstrates the segmental nature CD and the hyper-enhancement of the mesenteric blood vessels and thickened bowel…
Possible causes for change over time • Before 1970 – Retrospective data – Hospital based – Cross-sectional studies – Unclear definitions – Pre-endoscopic period • After 1970 – Early endoscopic period – Defined populations – Prospective registration – GP/hospital based • After…
Gender Female +2 HLA DR3 or DR4 +1 AP:AST (or ALT) ratio >3 <1.5 −2 +2 Immune disease Thyroiditis, colitis, others +2 γ-Globulin or IgG level above normal >2.0 1.5–2.0…
