Acid and Nonacid Reflux Monitoring
Detection of acid and nonacid reflux using esophageal reflux monitoring, which includes conventional and wireless pH monitoring and pH impedance, can be a valuable diagnostic tool when used appropriately in…
GASTROENTEROLOGY
Esophageal Manometry in Gastroesophageal Reflux Disease
High-resolution manometry (HRM) allows nuanced evaluation of esophageal motor function, and more accurate evaluation of lower esophageal sphincter (LES) function, in comparison with conventional manometry. Pathophysiologic correlates of gastroesophageal reflux…
Symptom Predictability in Gastroesophageal Reflux Disease and Role of Proton Pump Inhibitor Test
There are problems with the definition, assessment, and measurement of gastroesophageal reflux disease (GERD). The Reflux Disease Questionnaire and the GERD questionnaire are patient-reported outcome (PRO) measures for use in…
Barium Esophagram
The barium esophagram is an integral part of the assessment and management of patients with gastroesophageal reflux disease (GERD) before, and especially after, antireflux procedures. While many of the findings…
Role of Endoscopy in GERD
Endoscopy is commonly performed for the diagnosis and management of gastroesophageal reflux disease (GERD). Endoscopy allows the physician to evaluate esophageal mucosa for evidence of esophagitis and Barrett esophagus, to…
Pathophysiology of Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD) is one of the most common digestive diseases in the Western world, with typical symptoms, such as heartburn, regurgitation, or retrosternal pain, reported by 15% to…
Epidemiology of Gastroesophageal Reflux Disease
The prevalence of gastroesophageal reflux disease (GERD) symptoms increased approximately 50% until the mid-1990s, when it plateaued. The incidence of complications related to GERD including hospitalization, esophageal strictures, esophageal adenocarcinoma,…
What’s New in Gastroesophageal Reflux Disease for 2014
Joel E. Richter, MD, FACP, MACG, Editor It is my pleasure to present you with this issue of Gastroenterology Clinics of North America . The issue focuses on a common…
Gastroesophageal Reflux Disease
Gary W. Falk, MD, MS, Consulting Editor Gastroesophageal reflux disease (GERD) remains one of the most common problems encountered in gastrointestinal clinical practice with over 8 million patient visits in…
Genetic and Epigenetic Underpinnings of Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is a complex, polygenic disorder caused by genetic predisposition and environmental exposures. Because of the recent emergence of EoE as a bona fide global health concern, a…
