Crohn disease is a chronic inflammatory condition, affecting the entire gastrointestinal tract, that follows a relapsing and remitting course. Approximately two-thirds of patients with Crohn disease undergo a resective surgery…
Patients with longstanding, extensive ulcerative colitis are at increased risk of developing colorectal cancer. The risk is lower than previously reported, but colonoscopic surveillance is recommended still to detect intraepithelial…
Endoscopy plays an essential role in the diagnosis, management, and surveillance of inflammatory bowel disease (IBD). Endoscopy in combination with clinical findings, blood tests, and stool analysis can help establish…
Samir A. Shah, MD, Guest Editor Adam Harris, MD, Guest Editor Edward Feller, MD, Guest Editor The diagnosis and management of inflammatory bowel disease (IBD) is often complex. Better techniques…
Diarrhea is a common problem in patients with immunocompromising conditions. The etiologic spectrum differs from patients with diarrhea who have a normal immune system. This article reviews the most important…
Diarrhea is a common clinical feature of inflammatory bowel diseases and may be accompanied by abdominal pain, urgency, and fecal incontinence. The pathophysiology of diarrhea in these diseases is complex,…
Celiac disease is common, affecting approximately 1 in 100 people, yet it remains underdiagnosed. This article reviews our current understanding of celiac disease, diagnosis, and common pitfalls. Although the cornerstone…
This article will focus on the role of the colon in the pathogenesis of diarrhea in carbohydrate malabsorption or physiologically incomplete absorption of carbohydrates, and on the most common manifestation…
Circulating agents cause intestinal secretion or changes in motility with decreased intestinal transit time, resulting in secretory-type diarrhea. Secretory diarrhea as opposed to osmotic diarrhea is characterized by large-volume, watery…
Intestinal microflora can be considered an organ of the body. It has several functions in the human gut, mostly metabolic and immunologic, and constantly interacts with the intestinal mucosa in…
