Rome III IBS diagnostic criteria and IBS subtypes Criteria need to be fulfilled for the last 3 months with symptom onset at least 6 months prior to diagnosis IBS is…

Drugs: opiates, nonsteroidal anti-inflammatory, anticholinergic, antidepressant, antihistamine, anti-Parkinsonian, iron, calcium Neurogenic: autonomic neuropathy, Parkinson’s disease, multiple sclerosis, CNS and spinal cord lesions, pseudo-obstruction, diabetes mellitus, pelvic nerve damage Myogenic: connective…

Mucosal disorders  Esophagitis  Occult acid reflux disease  Gastritis  Duodenitis  Peptic ulcer disease  H. pylori infection  Gastric cancer Neuromuscular dysfunction  Gastroparesis  Visceral hypersensitivity  Impaired fundic relaxation  Abnormalities in the brain-gut axis…

Episodes of pain located in the epigastrium and/or right upper quadrant and all of the following: 1. Episodes lasting 30 min or longer 2. Recurrent symptoms occurring at different intervals (not daily)…

Medications and toxic etiologies  Cancer chemotherapy  Aspirin  Nonsteroidal anti-inflammatory drugs  Auranofin  Antigout drugs  Digoxin  Antiarrhythmics  Antihypertensives  β-Blockers  Calcium channel antagonists  Diuretics  Oral antidiabetics  Oral contraceptives  Erythromycin  Tetracycline  Sulfonamides  Antituberculous drugs…

Fig. 12.1 Representative CT image demonstrating marked diffuse dilation of the small bowel without transition point Introduction Intestinal pseudo-obstruction can be categorized as either acute or chronic. Chronic intestinal pseudo-obstruction…

Fig. 1.1 Assessment of nadir upper esophageal sphincter relaxation pressure using high-resolution esophageal manometry isobaric contour tool. (a) depicts a patient with normal upper esophageal sphincter relaxation. (b) depicts a…

Fig. 11.1 Normal microbial distribution along the length of the gastrointestinal tract Small intestinal bacterial overgrowth (SIBO) is characterized by the presence of increased numbers of colonic-type bacteria in the…