Fig. 1 Imaging, operative, gross, and histopathology of a liver GIST metastasis. (a) Preoperative MRI imaging of isolated peripheral liver metastasis, as noted by the arrow. (b) PET scan showing…

Site % Gastric 60–70 Small intestine 25–33  Jejunum/ileum 27  Duodenum 5 Rectum 3–10 Large intestine 3–5 Esophagus <1 Other intra-abdominal 8 Extra-abdominal <5 GIST tends to be quite friable and…

Fig. 1 Duodenal gastrointestinal stromal tumor with overlying normal mucosa Fig. 2 Gastrointestinal stromal tumor with overlying ulcers in the proximal gastric body 5.2 Endoscopic Ultrasonography Standard endoscopy provides imaging…

Fig. 1 Port placement and patient positioning for laparoscopic wedge resection [10] 2.2 Laparoendoscopic Technique This technique, as previously described [19], is for patients with predominantly intraluminal masses. Positioning is…

Fig. 1 CT characteristics of GISTs. (a) Polypoid gastric GIST (arrow), (b) Exophytic gastric GIST (c) Exophytic small bowel GIST fistulizing to the bowel lumen note the contrast within the…

Fig. 1 Surgical palliation refers to the use of a procedure with the intention of relieving symptoms, minimizing patient distress, increasing the durability of treatment, improving quality of life, decreasing…

Fig. 1 CT scans in a patient with gastroesophageal junction GIST (red circle) before (a) and after (b) 3 months of neoadjuvant imatinib, showing partial response Fig. 2 PET scans…

GIST subtype Molecular cause Usual age GIST presentation GIST location Pathology of GIST tumors Other cancers and clinical features Familial GIST Germline KIT or PDGFRA mutation 30–40 years Stomach or…

GIST location N Progression rate with full long-term follow-up Size <5 cm Size <5 cm Size >10 cm Size >10 cm <5 mitoses per 50 HPFs >5 mitoses per 50…