Charles J. Lightdale, MD, Consulting Editor Endoscopic ultrasound (EUS) started out as primarily an imaging technique, but it soon became clear that EUS-guided fine-needle aspiration (FNA) for tissue acquisition would…

Endoscopic submucosal dissection (ESD) improves the quality of life of patients with early gastric cancer (EGC) and dysplasia by preserving gastric function. ESD in the treatment of EGC and dysplasia…

Induced pluripotent stem (iPS) cells have captured the world’s attention and directed an unprecedented focus on regenerative medicine. The potential of iPS cells to aid in the development of new…

Submucosal endoscopy with a mucosal flap (SEMF) safety valve technique is a global concept in which the submucosa is a free working space for endoscopic interventions. A purposefully created intramural…

Peroral endoscopic myotomy (POEM) is an evolving minimally invasive endoscopic surgical procedure, with no skin incision, intended for long-term recovery from symptoms of esophageal achalasia. POEM was developed based on…

The number of medical facilities that perform colorectal endoscopic submucosal dissection (ESD) has been growing, and its effectiveness has been increasingly reported in recent years. Indications approved by the Japanese…

Duodenal endoscopic submucosal dissection (ESD) is technically difficult due to the unique anatomic features. The risks include intraprocedural complications, delayed bleeding, and perforation. A small-caliber-tip transparent hood is useful. Mechanical…

Endoscopic mucosal resection (EMR) of early gastric cancer, which has been proved to be safe and effective and is the established standard of care in Japan, has become increasingly established…

The advantage of endoscopic submucosal dissection (ESD) is the ability to achieve high R0 resection, providing low local recurrence rate. Esophageal ESD is technically more difficult than gastric ESD due…