Introduction Hematopoietic stem cell transplantation (HSCT) is commonly used as a treatment for malignant and nonmalignant diseases. Over the past decade, there has been more focus on the chronic complications…
Introduction Since 1957, when the first bone marrow transplantation was performed by Thomas et al., hematopoietic stem cell transplantation (HSCT) has been used for the treatment of several hematologic and…
Introduction Hematopoietic stem cell transplantation (HSCT) is a potentially curative therapy for patients with hematologic malignancies, bone marrow failure syndromes, immunodeficiency states, and metabolic disorders. Thrombotic microangiopathy (TMA) is a…
Introduction Kidney function in oncologic patients is an important parameter for several reasons. In some specific cases, like urologic cancers, the tumor itself can cause acute or chronic kidney dysfunction….
Hyponatremia Hyponatremia and cancer relationship Hyponatremia is the most common electrolyte abnormality observed in cancer patients. In a retrospective cohort study from a comprehensive cancer center, hyponatremia (serum Na +…
Introduction Disturbances in calcium and phosphorus homeostasis are commonly encountered when caring for cancer patients. These may result from the malignancy itself or as a complication of the treatment process….
Introduction Potassium abnormalities, both hypo- and hyperkalemia, can occur with significant consequences in patients with malignancies. In addition to typical causes of disturbances in potassium homeostasis, there are unique etiologies…
Fibrillary glomerulonephritis Overview and epidemiology Fibrillary glomerulonephritis (FGN) was first described in 1977. It is a rare disease, with incidence of less than 1% of native kidney biopsies. It is…
Introduction Systemic amyloidoses encompass a group of diseases characterized by deposition of abnormal, insoluble, misfolded, β-pleated protein fibrils in different organs. Amyloid protein positively stains with Congo red and demonstrates…
Introduction Sinusoidal obstruction syndrome (SOS) is a well-described complication of the high-dose conditioning regimens used in hematopoietic stem cell transplantation (HSCT), as well as certain hepatotoxic chemotherapies or radiation therapy…
