Psychological/Social Aspects
The phenomenal success of pediatric liver transplantation (LT) for the treatment of end-stage liver disease over the last 30 years has changed how we define their optimal outcome. Increasing surgical…
Preparation for Pediatric Liver Transplant: Medical Aspects
Introduction Optimal preparation for pediatric liver transplantation (PLT) is accepted to be one of the cornerstones of favorable outcomes. Preparation depends on many factors spanning timely referral to emergent management…
Indications and Contraindications for Pediatric Liver Transplant
Introduction Liver transplantation has become the standard of care for children with an array of disease processes. Collectively, progressive hepatic disease with complications of end-stage liver disease (ESLD), metabolic disease…
Managing a Scarce Resource in Pediatric Liver Transplantation
Introduction For many end-stage organ diseases, transplantation remains the most effective and often the only option for curative treatment. This is especially true for liver disease, where supportive care and…
Health System Requirements for Pediatric Liver Transplantation
Introduction The ultimate goal for a pediatric liver transplant (LT) program is for transplant recipients to live a normal lifespan free from disease recurrence or long-term morbidity. The healthcare needs…
What Is Different Between Pediatric and Adult Liver Transplantation?
Introduction Clinical liver transplantation stems from the pioneering work of Professor Thomas Starlz in Denver, Colorado, where he attempted the first human liver transplantation on March 1, 1963. The recipient…
Brief History of Pediatric Liver Transplantation
Principal Historical Milestones and Breakthroughs Technical Aspects The basic technique of orthotopic liver transplantation was developed in dogs by Thomas E. Starzl in the early 1960s; the dog I watched…
Resources for the gastroparesis patient
Introduction Gastroparesis, also called delayed gastric emptying, is a chronic digestive condition where the stomach fails to properly empty, causing sometimes debilitating symptoms, including nausea, vomiting, pain, and distention/bloating, which…
Cell transplantation for gastroparesis
Introduction Normal gastric motor function requires coordinated interaction between the central nervous system (CNS), the enteric nervous system (ENS), interstitial cells of Cajal (ICC), and smooth muscle cells (SMCs). Gastroparesis…
Female predominance in gastroparesis
Key points • Epidemiological studies show that the incidence of gastroparesis in women is four times higher than men. • Female sex hormones fluctuate during different hormonal stages including the…
