Sphincter of Oddi Dysfunction
Sphincter of Oddi Dysfunction DEFINITION: The Sphincter of Oddi (SO) is a fibromuscular sheath that encircles the terminal portion of the common bile duct, pancreatic duct, and common channel in…
Pancreatitis: Chronic
Pancreatitis: Chronic DEFINITION: Chronic Pancreatic (CP) implies the presence of parenchymal fibrosis, and loss of glandular function Marseilles-Rome/Sarles classification: Lithogenic (Calcifying) CP: Largest group, ETOH is leading cause and is…
Pancreatitis: Acute
Pancreatitis: Acute (Am J Gastroenterol 2006;101:2379-2400 & 1997;92:377-86. N Engl J Med 2006;354:2142-50. J Hepatobil Pancreat Surg 2006;13:56-60) DEFINITION: Acute pancreatitis: inflammatory condition of the pancreas that may extend to…
Pancreatic Carcinoma
Pancreatic Carcinoma (Gastroenterology 1999;117:1463-84) DEFINITION: Adenocarcinoma, well-differentiated, arising from pancreatic ductal epithelium (90% of cases) Most arise in the head of pancreas (80%) See also Pancreas/Biliary- Cystic Disease of the…
Cystic Disease of the Pancreas
Cystic Disease of the Pancreas (Surgical Oncology 2005;14:155-78. Pancreas 2002;25:217-21) DEFINITION: True pancreatic cyst has epithelia cell lining (account for only 10-15% of all cystic lesions of the pancreas) Pancreatic…
Cholelithiasis & Choledocholithiasis
Cholelithiasis & Choledocholithiasis CHOLELITHIASIS Definition: “Gallstones” “Sludge” (microlithiasis): super-concentrated mixture of bile acids, bilirubin, cholesterol, mucus, and proteins Discharge into cystic duct & CBD can cause Acalculous Cholecystitis or ‘Idiopathic…
Cholecystitis & Cholangitis
Cholecystitis & Cholangitis CHOLECYSTITIS Definition: Inflammation of the gallbladder Etiologies: E. coli, Klebsiella, Enterococcus, and Enterobacter are the usual pathogens DDX: hepatitis, liver mets, pancreatitis, pseudocyst, PUD, pyelonephritis, renal stones,…
Cholangiocarcinoma
Cholangiocarcinoma DEFINITION: Bile duct cancers that arise from the epithelial cells of the bile ducts (does not include gallbladder or ampullary cancer) Classification: Intrahepatic: originate from small or large intrahepatic…
Wilson’s Disease
Wilson’s Disease (Hepatology. 2003;37:1475-92) DEFINITION: Autosomal recessive inherited disorder of copper overload secondary to deficiency of an enzyme derived from liver cells (↓ secretion) Other inheritable forms of liver disease:…
