Gastrointestinal motility disorders affect the neuromuscular functions needed for movement of contents through the gastrointestinal tract. This definition excludes strictures and other mechanical causes for impaired passage from the concept…
This issue of Gastroenterology Clinics of North America is focused on challenges faced in everyday clinical practice. Thus rather than reviewing the evolving research literature that details the many experimental…
Eamonn M.M. Quigley, MD, FRCP, FRCPI Guest Editor The study of gastrointestinal motility and those disorders that result from its disordered function has, for far too long, been a much…
Pancreatic ductal adenocarcinoma comprises more than 90% of pancreatic tumors. It is the 10th most common cancer diagnosis in the United States, but represents the fourth most common cause of…
Pancreatic adenocarcinoma is the fourth leading cause of cancer death in the United States, with a 5-year survival rate of 5.6%. One third of pancreatic cancer patients have local or…
Surgical resection remains an important component in the treatment of pancreatic cancer. Unfortunately, only approximately 10% to 20% of patients are eligible for surgical resection at presentation. Many patients with…
Pancreatic adenocarcinoma (PC) is the fourth leading cause of cancer death and is associated with an extremely poor prognosis: The 5-year survival probability is less than 5% for all stages…
According to the American Cancer Society, 43,140 new cases and 36,800 deaths from pancreatic cancer were expected in 2010. The incidence of pancreatic adenocarcinoma in the United States decreased by…
Clinical Overview Each year in the United States, more than 40,000 patients are diagnosed with pancreatic cancer and a nearly equal number will die from their disease. Pancreatic cancer is…
In the early part of the 20th century, many research groups were trying to isolate insulin from the other digestive proteins of the pancreas. In 1921, Fredrick Banting and his…
