Charles J. Lightdale, MD, Consulting Editor The small intestine—with its daunting length and sharp turns—was an impossible barrier to cross in early gastrointestinal endoscopy. The emerging technologies of video capsule…
Intragastric devices may be of benefit to patients who are unable to achieve weight loss through lifestyle modification and pharmaceuticals. With the help of every member of a multidisciplinary team…
The recent increase in US Food and Drug Administration-approved weight-loss devices has diversified obesity treatment options. The regulatory pathways for endoscopically placed weight-loss devices and considerations for clinical trials are…
Obesity in children and adolescents is a severe health, psychosocial, and economic problem. Treatment of obesity should be based on the physiology, biochemistry, and genetics of the disease. Treatment is…
The duodenum has become recognized as a metabolic signaling center that is involved in regulating insulin action and, therefore, insulin resistance states such as type 2 diabetes. Bariatric surgery and…
The small bowel is a prime target for bariatric and metabolic endoscopic therapies. New insights into the mechanisms of action of surgical therapies have led to new endoscopic therapies for…
Aspiration therapy is a weight loss therapy in the United States for patients with a body mass index between 35 kg/m 2 and 55 kg/m 2 . Aspiration therapy allows patients…
This article focuses on the stomach target devices that are currently in various stages of development. Approved intragastric balloons, devices targeting small bowel and aspiration techniques, are described in other…
Endoscopic gastric plication techniques are effective for weight loss. These procedures offer the potential for higher efficacy than conservative modalities, such as medications and lifestyle modifications, and lower invasiveness than…
Cost-effective therapies to address the growing epidemic of obesity are a leading priority in modern medicine. Intragastric balloons (IGBs) are one such option, with increased effectiveness compared with pharmacotherapy and…
