The general principles for performing a laparoscopic operation have not changed significantly since the laparoscopic revolution began in the late 1980s. Prior to the laparoscopic procedure, a preoperative conference should…
Abstract The rarity and diversity of liver tumors in children means that no center has adequate experience to deliver optimal care to every patient. Hence cooperative study groups have been…
Abstract Both systemic and local infections caused by bacterial, fungal, and parasitic agents may cause significant hepatic dysfunction. This chapter will attempt to delineate clinical syndromes caused by some of…
Abstract Fibrocystic liver disease refers to a heterogeneous group of disorders with shared, but also distinct, pathophysiologic and clinical features. Cystic dilatation of intrahepatic bile duct structures and variable degrees…
Abstract Management in the early postoperative period requires the coordinated efforts of the transplant team and the pediatric intensive care staff, and other key ancillary services, such as interventional radiology,…
Abstract Liver transplantation is the standard of care for end-stage liver disease in children and the vast majority of transplant recipients experience successful outcomes. Better preoperative care, enhanced surgical techniques,…
Abstract Pathologies of mitochondrial structure and function are now recognized as the etiology of a growing list of monogenic mitochondrial disorders as well as contributing to many common diseases. Studying…
Abstract The importance of bile acid synthesis and metabolism to normal physiology and their role in pathophysiological states is well recognized. For such small and relatively simple molecules, bile acids…
Abstract The liver is the largest parenchymal organ in the body and has a complicated circulatory system, with dual afferent blood supply from the portal vein and hepatic artery. Although…
Abstract Non-alcoholic fatty liver disease (NAFLD) is now the most common cause of chronic liver disease in both adults and children worldwide [1]. Increasing industrialization and commercial globalization in Asia,…
