Introduction Acute kidney injury (AKI) occurs commonly in cancer patients and independently increases morbidity and mortality. , Despite impressive gains in the understanding of the basic pathophysiologic principles underlying kidney…
Introduction Acute and chronic renal impairment resulting from urinary tract obstruction is common among patients with cancer and not solely limited to patients with pelvic tumors. Unlike benign causes of…
Introduction Tuberous sclerosis complex (TSC) is an often underdiagnosed and misunderstood disease affecting more than one million patients worldwide. Disruptions in the TSC axis lead to cellular abnormalities that result…
Introduction Tumor lysis syndrome (TLS) describes the series of metabolic events that result from the death of rapidly dividing cancer cells. When cancer cells die, either spontaneously or in response…
Introduction Epidemiology and risk factors Renal cell carcinoma (RCC) is the eighth most common malignancy in the world. According to the National Cancer Institute, in 2017 approximately 64,000 diagnoses were…
Introduction Advances in therapy, risk stratification, and supportive care have improved survival of patients with cancer over the past 2 decades. Acute kidney injury (AKI) remains a common complication of…
Introduction Kidney cancer, or renal cell carcinoma (RCC), is the most common malignancy seen in the practice of nephrology. It is one of the relatively few cancers whose incidence is…
Introduction Nephroblastoma, or Wilms tumor (WT), is the most common primary renal malignancy in childhood and represents 6% of all childhood cancers. WTs comprise over 95% of all kidney tumors…
Definition Radiation nephropathy is the kidney parenchymal injury and loss of function caused by radiation exposure to the kidneys. Its typical form is caused by external beam ionizing radiation, by…
Paraneoplastic glomerulopathy remains a rare clinical entity. Please refer to Chapters 22 and 23 for a more detailed discussion on the reported prevalence and some of the purported mechanisms for…
