Benefits Drawbacks Earlier control of electrolyte/metabolic derangement Iatrogenic episodes of hemodynamic instability that may impede kidney repair and recovery Earlier control of acid–base derangement Insertion of dialysis catheter and risk…
and Rinaldo Bellomo6 (5) Division of Nephrology, Department of Medicine, National University Hospital, Singapore, Singapore (6) Department of Intensive Care, Austin Hospital, 145 Studley Road, Level 2 Austin Tower, Heidelberg, VIC,…
score 2 points 1 point zero Thrombocytopenia ×10 9 l 20–100 or Fall > 50 % 10 – 19 or Fall 30–50 % <10 or Fall <30 % Timing of onset in…
Cardiorenal syndrome (CRS) A complex pathophysiological disorder of the heart and kidneys whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction in the other organ…
Provision of information above and beyond serum creatinine and/or urine output Non-invasive test using easily accessible samples Results rapidly available Specific cut-off values to distinguish between normal and abnormal renal…
(8.1) Where [Creat]P is the plasma concentration of creatinine (in μmol/ml) and G the creatinine generation rate in μmol/min. Thus at steady state a lower GFR will be associated with…
© Springer International Publishing 2015Heleen M. Oudemans-van Straaten, Lui G. Forni, A.B. Johan Groeneveld, Sean M. Bagshaw and Michael Joannidis (eds.)Acute Nephrology for the Critical Care Physician10.1007/978-3-319-17389-4_13 13. Dose of Renal Replacement Therapy in AKI Catherine S. C. Bouman1 , Marlies Ostermann2 , Michael Joannidis3 …
Patient factors Advanced Age Female Black Race Pre-existing co-morbidities Chronic Kidney Disease (CKD) Liver Disease Respiratory Disease Heart Failure Diabetes: Especially with proteinuria Cancer Current susceptibilities Volume Depletion Dehydration Hypoalbuminemia…
Fig. 2.1 Proportion of patients (%) with different acute kidney injury (AKI) stages, according to the recent new classifications (RIFLE/AKI/KDIGO) Plausible explanations for differences in reported incidences between studies are…
Fig. 4.1 An overview of the systems affecting renal blood flow and metabolism in sepsis The renin–angiotensin–aldosterone system (RAAS) is activated during sepsis and hypotension. Renin release is stimulated by…
