Differences in Etiology and Treatment in Japan
Year 1977 1983 1985 1988–1989 1997 2005 2006 Author [Ref] Ueda [1] Kitajima [2] Glassock [3] Yoshikawa [4] Koyama [5] Nozawa [9] Wakai [7] Source of patients Tokyo Jikei U…
The Implication of the KDIGO Clinical Practice Guidelines on Management of IgA Nephropathy
Recommendation Long-term ACEI or ARB or ARB treatment when proteinuria is >1 g/day, with up-titration of the drug depending on blood pressure (1B) Suggestions Proteinuria ACEI or ARB if proteinuria is…
Limitations of RAS Blockade in IgA Nephropathy
Chapter Recommendation statement Grade 10.2 Antiproteinuric and antihypertensive therapy 10.2.1 We recommend long-term ACEI or ARB treatment when proteinuria is >1 g/day, with up-titration of the drug depending on blood pressure…
Differences in Etiology and Treatment in Scandinavian Countries
© Springer Japan 2016Yasuhiko Tomino (ed.)Pathogenesis and Treatment in IgA Nephropathy10.1007/978-4-431-55588-9_13 13. Differences in Etiology and Treatment in Scandinavian Countries Jukka Mustonen1, 2 , Kati Kaartinen3, Jaana Syrjänen2 and Ilkka Pörsti1, 2 (1) School of Medicine, University of Tampere,…
M-type Phospholipase A2 Receptor (PLA2R) and Thrombospondin Type-1 Domain-Containing 7A (THSD7A) in Membranous Nephropathy
Fig. 11.1 Membranous nephropathy. (a–b) Light microscopy showing thickened glomerular basement with pin holes and spikes ((a) periodic acid-Schiff stain, (b) silver methenamine stain, both 40×). (c) Immunofluorescence microscopy showing…
Angiopoietin-Like 4 (Angptl4) in MCNS
Fig. 3.1 Pathobiology of circulating Angptl4 in nephrotic syndrome (From [21]). Diagram representing the production of circulating Angptl4 protein and its biological effects. The circulating, sialylated form of Angptl4 is…
Hemopexin in Minimal Change Nephrotic Syndrome
Fig. 2.1 Electron micrographs of glomerular capillary segments from sections of rat kidney following infusion in vivo with either Hpx (a) or heat-inactivated Hpx (HI-Hpx) (b). The tissue samples were…
The Role of c-mip in the Pathogenesis of Minimal Change Nephrotic Syndrome
Fig. 6.1 Current pathophysiological hypotheses involved in relapsing idiopathic nephrotic syndrome (INS). Clinical and experimental observations suggest that lymphocytes and podocyte disturbances are two sides of relapsing INS. Besides T-lymphocyte…
Cationic Bovine Serum Albumin as Cause of Membranous Nephropathy: From Mice to Men
Fig. 12.1 Results of two-dimensional electrophoresis and immunoblot demonstrating that circulating albumin in children migrates in the basic range of pH (lane 1–4) (Debiec et al. [18]) Fig. 12.2 Expression…
Co-stimulatory Molecule CD80 (B7.1) in MCNS
© Springer Japan 2016Kazunari Kaneko (ed.)Molecular Mechanisms in the Pathogenesis of Idiopathic Nephrotic Syndrome10.1007/978-4-431-55270-3_4 4. Co-stimulatory Molecule CD80 (B7.1) in MCNS Michiko Shimada1 , Takuji Ishimoto2 and Richard J. Johnson3 (1) Division of Cardiology and Nephrology, Hirosaki University Graduate…
