Is IgA Nephropathy a Single Disease?
Fig. 1.1 Geographical variations in the prevalence of IgAN. Percentages represent the proportion of cases of IgAN compared to all native kidney biopsies performed. The numbers in brackets represent minority…
Podocyte Injury and Significance of Urinary Podocalyxin and Megalin
Fig. 6.1 The number of urinary podocytes in patients with IgAN with segmental sclerosis was higher than those in patients without (Modified from Ref. [12]) To more easily interpret the…
Japanese Clinical Practice Guidelines for IgA Nephropathy: Difference from KDIGO Guidelines
Fig. 15.1 Working group for the development of Clinical Guidelines for IgA Nephropathy, Progressive Renal Diseases Research by the Japanese Society of Nephrology, and Research on Intractable Disease by the…
The Differences in Etiology and Treatment of IgA Nephropathy in Korea
Reference Molecule Number of patients Polymorphism Vs. normal control F/U duration (months) Renal progression Biology Lim et al. [22] Clara cell secretory protein N = 267 G38A No difference 103.8 ± 52.6 AA genotype…
Is Tonsillectomy a Possible Treatment for IgA Nephropathy from Randomized Controlled Trial (RCT)?
Fig. 19.1 Trial profile The two groups did not differ in age, gender distribution, eGFR, urinary protein excretion, blood pressure, the proportion of patients’ given renin-angiotensin system (RAS) inhibitors, and…
Is IgA Nephropathy (IgAN) a Familial or Sporadic Disease?
Family history 1992–2000 2001–2010 With GN 95/908 (10.5 %) 77/822 (9.5 %) With dialysis 42/908 (4.6 %) 58/822 (7.1 %) Number of positive case/total number (%) Clinical phenotype of familial IgAN is generally similar…
Beyond the Differences in Tonsillectomy in IgA Nephropathy: From Rationale To Indications in Patients
© Springer Japan 2016Yasuhiko Tomino (ed.)Pathogenesis and Treatment in IgA Nephropathy10.1007/978-4-431-55588-9_18 18. Beyond the Differences in Tonsillectomy in IgA Nephropathy: From Rationale To Indications in Patients Yusuke Suzuki1 , Rosanna Coppo2 and Yasuhiko Tomino1 (1) Division of Nephrology,…
How Different Are the Current Understandings of Treatments for IgA Nephropathy?
Fig. 8.1 Answers selected by the audience for Case 1 In January 2014, BP 124/68, proteinuria 1.5 g/day, urinary RBC 5-9/HPF, eGFR 55 mL/min/1.73 m2. Renal biopsy: acute lesion (endocapillary hypercellularity) (+), chronic…
Advances in Genetics of Immunoglobulin A Nephropathy
Fig. 2.1 Surface interpolation of the standardized genetic risk score over Africa and Euroasia (main) and the Americas (inset). Symbols represent the locations of sampled populations [164] 2.3.4 Shared Genetics…
What Is the Goal for Proteinuria in IgA Nephropathy?
Authors Proposed target proteinuria Study design and characteristics of the cohort Partial remission or clinical remission Definition of proteinuria remission, g/day Timing of proteinuria measurements taken as a surrogate marker…
