Genetics, Screening, and Chemoprevention
Fig. 5.1 Schematic of the adenoma-to-carcinoma sequence in the development of colorectal cancer. The primary genes that are mutated related to each step are indicated (See text for abbreviations and…
Patient Surveillance After Curative-Intent Treatment for Rectal Carcinoma
Study, year Surveillance intensity Number of patients randomized Median observation time (months) Overall recurrence rate (%) Number of second bowel cancers Radical reoperation rate (%) 5-year survival rate (%) Ohlsson…
Postoperative Chemoradiation for Rectal Cancer
Trial No. of pts Randomization TME 5 year LR 5 year DFS 5 year OS Remarks GITSG 7175 (GITSG 1985) [2] 227 (i) Surgery alone No 24 % 45 %…
Anorectal Reconstruction
Fig. 16.1 Gracilus wrap around the colon: (a) alpha loop; (b) gamma loop; (c) epsilon loop Graciloplasty is technically easier than gluteoplasty and achieves better functional results [52]. Dynamic graciloplasty…
The Evolving Treatment of Rectal Cancer
© Springer-Verlag London 2015Walter E. Longo, Vikram Reddy and Riccardo A. Audisio (eds.)Modern Management of Cancer of the Rectum10.1007/978-1-4471-6609-2_1 1. The Evolving Treatment of Rectal Cancer Jorge L. Reguero1 and Walter E. Longo2 (1) Department of Surgery, Yale University School…
Epidemiology and Burden of Rectal Cancer
Activity Time Cost/charges Diagnosis 1–2 weeks $500 Staging 2 weeks $3,000 CT scan, MRI, U/S Consults/MDT 1 week $500 Radiotherapy Short course : 5 days $2,000 Long course : 5…
Transanal Minimally Invasive Surgery for Rectal Cancer
Fig. 9.1 Advantage of transanal minimally invasive surgery (TAMIS) for rectal cancer. Compared with the conventional laparoscopic approach, the TAMIS approach offers an in-line vantage point to the distal rectum,…
Laparoscopic Left-Sided Colectomy (Mobilization of Splenic Flexure and Sigmoidectomy)
Fig. 5.1 Positioning and instruments. The patient is placed in a modified lithotomy position using a levitator, with both arms fixed to the body trunk. Shoulder pads are used to…
Laparoscopic Right Lateral Pelvic Lymph Node Dissection (LPLND) with Pelvic Autonomic Nerve Preservation
Fig. 7.1 Port placement and surgeon’s standing position The right pelvic nerve plexus is dissected caudally along the pelvic wall side of the plexus, and thus, the internal margin of…
Robotic Total Mesorectal Excision
Fig. 10.1 Positioning and instruments used in robot-assisted total mesorectal excision. The patient is placed in a modified lithotomy position using a levitator with both arms fixed to the body…
